Erythropoietin (EPO) promotes neuronal survival after hypoxia and other metabolic insults
by largely unknown mechanisms. Apoptosis and necrosis have been proposed as …

Ischemic brain injury resulting from stroke arises from primary neuronal losses and by
inflammatory responses. Previous studies suggest that erythropoietin (EPO) attenuates both …

In recent work we reported that systemically administered erythropoietin (EPO) crosses the
blood–brain barrier and has protective effects in animal models of cerebral ischemia, brain …

Erythropoietin (EPO), a member of the type 1 cytokine superfamily, plays a critical hormonal
role regulating erythrocyte production as well as a paracrine/autocrine role in which locally …

Riluzole exerts a neuroprotective effect through different mechanisms, including action on
glutamatergic transmission. We investigated whether this drug affects glutamate transporter-…

Clinical data indicate that hydroalcoholic extracts of Hypericum perforatum might be as valuable
as conventional antidepressants in mild-to-moderate depression, with fewer side effects…

Glutamate‐induced excitotoxicity is suggested to play a central role in the development of
amyotrophic lateral sclerosis (ALS), although it is still unclear whether it represents a primary …

1 The mechanism underlying 5‐hydroxytryptamine (5‐HT) and/or dopamine release
induced by (+)‐amphetamine ((+)‐Amph), 3,4‐methylendioxymethamphetamine (MDMA), p‐…

The synthesis, pharmacological evaluation, and structure−activity relationships (SARs) of a
series of novel pyrroloquinoxalines and heteroaromatic-related derivatives are described. …

Chronic treatment with asialo erythropoietin (ASIALO-EPO) or carbamylated erythropoietin (CEPO)
improved motor behavior and reduced motoneuron loss and astrocyte and microglia …