Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non …
…, A Sadiq, A Sandler, W Lin, TO Lohmann… - The Lancet …, 2019 - thelancet.com
Background Atezolizumab (a monoclonal antibody against PD-L1), which restores anticancer
immunity, improved overall survival in patients with previously treated non-small-cell lung …
immunity, improved overall survival in patients with previously treated non-small-cell lung …
C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABAB receptors
…, G Rovelli, J Mosbacher, T Lohmann… - Journal of …, 2001 - Soc Neuroscience
Assembly of fully functional GABA B receptors requires heteromerization of the GABA B(1)
and GABA B(2) subunits. It is thought that GABA B(1) and GABA B(2) undergo coiled-coil …
and GABA B(2) subunits. It is thought that GABA B(1) and GABA B(2) undergo coiled-coil …
The anticonvulsant gabapentin (Neurontin) does not act through γ-aminobutyric acid-B receptors
…, J Mosbacher, S Elg, K Lingenhoehl, T Lohmann… - Molecular …, 2002 - ASPET
The actions of the anticonvulsant gabapentin [1-(aminomethyl)cyclohexaneacetic acid,
Neurontin] have been somewhat enigmatic until recently, when it was claimed to be a γ-…
Neurontin] have been somewhat enigmatic until recently, when it was claimed to be a γ-…
[HTML][HTML] Muscle IGF-1-induced skeletal muscle hypertrophy evokes higher insulin sensitivity and carbohydrate use as preferential energy substrate
…, MO Ribeiro, MM Okamoto, TH Lohmann… - BioMed Research …, 2015 - hindawi.com
We characterized the metabolic profile of transgenic mice exhibiting enhanced muscle
mass driven by increased mIGF-1 expression (MLC/mIGF-1). As expected, 6-month-old MLC/mIGF…
mass driven by increased mIGF-1 expression (MLC/mIGF-1). As expected, 6-month-old MLC/mIGF…
A comparative non-radioactive in situ hybridization and immunohistochemical study of the distribution of α7 and α8 subunits of the nicotinic acetylcholine receptors in …
THO Lohmann, AS Torrão, LRG Britto, J Lindstrom… - Brain research, 2000 - Elsevier
The distribution of mRNA transcripts corresponding to the α7 and α8 subunits of the nicotinic
acetylcholine receptors (nAChRs) was studied in selected structures of the chick visual …
acetylcholine receptors (nAChRs) was studied in selected structures of the chick visual …
Abstract CT200: IMpower130: Progression-free survival (PFS) and safety analysis from a randomized phase 3 study of carboplatin+ nab-paclitaxel (CnP) with or …
…, A Zer, N Reinmuth, A Sadiq, V Archer, TO Lohmann… - Cancer Research, 2019 - AACR
Background: Atezolizumab (atezo) (anti-PD-L1) monotherapy improves overall survival (OS)
vs docetaxel in 2L+ NSCLC regardless of PD-L1 status; phase 3, 1L studies have shown …
vs docetaxel in 2L+ NSCLC regardless of PD-L1 status; phase 3, 1L studies have shown …
Mice presenting skeletal muscle hypertrophic phenotype driven by mIGF‐1 over‐expression have improved carbohydrate metabolism and insulin sensitivity.
…, MM Okamoto, A Turri, TO Lohmann… - The FASEB …, 2009 - Wiley Online Library
Objective In this study, we aim to characterize the metabolic profile of mice presenting higher
muscle mass driven by mIGF‐1, a muscle specific trophic factor. Methods WT and mIGF‐1 …
muscle mass driven by mIGF‐1, a muscle specific trophic factor. Methods WT and mIGF‐1 …
Alectinib in Resected ALK-Positive Non–Small-Cell Lung Cancer
…, S Lu, Q Wang, T Ochi Lohmann… - … England Journal of …, 2024 - Mass Medical Soc
Background Platinum-based chemotherapy is the recommended adjuvant treatment for patients
with resectable, ALK-positive non–small-cell lung cancer (NSCLC). Data on the efficacy …
with resectable, ALK-positive non–small-cell lung cancer (NSCLC). Data on the efficacy …
Bitopertin in negative symptoms of schizophrenia—results from the phase III FlashLyte and DayLyte studies
…, S Lawrie, J Napieralski, T Ochi-Lohmann… - Biological …, 2017 - Elsevier
Background There is currently no standard of care for treatment of negative symptoms of
schizophrenia, although some previous results with glutamatergic agonists have been …
schizophrenia, although some previous results with glutamatergic agonists have been …
Bayesian dosimetry II: Credibility intervals for radiation dose
MR Madruga, TH OCHI‐LOHMANN, K Okazaki… - …, 1996 - Wiley Online Library
This paper is the natural sequel to Madruga et al.(Environmetrics5, 47–56 (1994)) where data
from literature were analysed. Here, three sets of experimental data were obtained at IPEN …
from literature were analysed. Here, three sets of experimental data were obtained at IPEN …