[HTML][HTML] The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to …

…, FO Goda, EI Christensen, TG Hammond… - Journal of Biological …, 1998 - ASBMB
The present report shows the molecular characterization of the rat 460-kDa epithelial
glycoprotein that functions as the receptor facilitating uptake of intrinsic factor-vitamin B 12 …

Differences in susceptibility to tumor necrosis factor α-induced apoptosis among MCF-7 breast cancer cell variants

…, GL Navar, S Krajewski, JC Reed, TG Hammond… - Cancer research, 1998 - AACR
Widespread use of MCF-7 human breast carcinoma cells as a model system for breast cancer
has led to variations in these cells between different laboratories. Although several reports …

Effects of spaceflight on murine skeletal muscle gene expression

…, S Morony, DL Lacey, TG Hammond… - Journal of Applied …, 2009 - journals.physiology.org
Spaceflight results in a number of adaptations to skeletal muscle, including atrophy and shifts
toward faster muscle fiber types. To identify changes in gene expression that may underlie …

Selectivity of chlorantraniliprole to parasitoid wasps

…, P Suvagia, G Walker, TG Hammond - Pest Management …, 2010 - Wiley Online Library
BACKGROUND: Chlorantraniliprole is a novel anthranilic diamide insecticide registered for
use in vegetables, fruits, grains and turf against a variety of insect pests. The objective of this …

Myeloma light chains are ligands for cubilin (gp280)

…, M Lyles, J Bruno, TG Hammond - American Journal …, 1998 - journals.physiology.org
Although myeloma light chains are known to undergo receptor-mediated endocytosis in the
kidney, the molecular identity of the receptor has not been characterized. We examined the …

Ang II Accumulation in Rat Renal Endosomes During Ang II-Induced Hypertension: Role of AT1 Receptor

JL Zhuo, JD Imig, TG Hammond, S Orengo, E Benes… - …, 2002 - Am Heart Assoc
Hypertension induced by long-term infusion of angiotensin II (Ang II) is associated with
augmented intrarenal Ang II levels to a greater extent than can be explained on the basis of the …

Megalin mediates renal uptake of heavy metal metallothionein complexes

…, S Atrian, PL Allen, TG Hammond - American Journal …, 2004 - journals.physiology.org
Although several heavy metal toxins are delivered to the kidney on the carrier protein
metallothionein (MT), uncertainty as to how MT enters proximal tubular cells limits treatment …

Time course of LPS-induced gene expression in a mouse model of genitourinary inflammation

…, NB Nguyen, J Winston, TG Hammond… - Physiological …, 2001 - journals.physiology.org
In this study, self-organizing map (SOM) gene cluster techniques are applied to the analysis
of cDNA microarray analysis of gene expression changes occurring in the early stages of …

Light chains are a ligand for megalin

…, K Crenshaw, TG Hammond - Journal of applied …, 2005 - journals.physiology.org
Cubilin and megalin are giant glycoprotein receptors abundant on the luminal surface of
proximal tubular cells of the kidney. We showed previously that light chains are a ligand for …

Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor.

…, SK Moestrup, TG Hammond… - The Journal of …, 1997 - Am Soc Clin Investig
Previous studies in the rat have shown that antibodies to gp280, a protein > 200 kD and
closely associated with the early endocytic system can induce fetal malformations. Although …