[HTML][HTML] The heptahelical domain of GABAB2 is activated directly by CGP7930, a positive allosteric modulator of the GABAB receptor

V Binet, C Brajon, L Le Corre, F Acher, JP Pin… - Journal of Biological …, 2004 - ASBMB
The γ-aminobutyric acid, type B (GABA B ) receptor is well recognized as being composed
of two subunits, GABA B1 and GABA B2 . Both subunits share structural homology with other …

Allosteric functioning of dimeric class CG‐protein‐coupled receptors

JP Pin, J Kniazeff, J Liu, V Binet, C Goudet… - The FEBS …, 2005 - Wiley Online Library
Whereas most membrane receptors are oligomeric entities, G‐protein‐coupled receptors
have long been thought to function as monomers. Within the last 15 years, accumulating data …

Activation mechanism of the heterodimeric GABAB receptor

JP Pin, J Kniazeff, V Binet, J Liu, D Maurel… - Biochemical …, 2004 - Elsevier
The GABA B receptor was the first heteromeric G-protein coupled receptor (GPCR) identified.
Indeed, both GABA B1 and GABA B2 subunits appear necessary to get a functional GABA …

Real-time analysis of agonist-induced activation of protease-activated receptor 1/Gαi1 protein complex measured by bioluminescence resonance energy transfer in …

MA Ayoub, D Maurel, V Binet, M Fink, L Prézeau… - Molecular …, 2007 - ASPET
G protein-coupled receptors transmit extracellular signals into the cells by activating
heterotrimeric G proteins, a process that is often followed by receptor desensitization. Monitoring …

[HTML][HTML] Common structural requirements for heptahelical domain function in class A and class CG protein-coupled receptors

V Binet, B Duthey, J Lecaillon, J Quoyer… - Journal of biological …, 2007 - ASBMB
G protein-coupled receptors (GPCRs) are key players in cell communication. Several
classes of such receptors have been identified. Although all GPCRs possess a heptahelical …

Oct-1 potentiates CREB-driven cyclin D1 promoter activation via a phospho-CREB-and CREB binding protein-independent mechanism

S Boulon, JC Dantonel, V Binet, A Vié… - … and cellular biology, 2002 - Taylor & Francis
Cyclin D1, the regulatory subunit for mid-G 1 cyclin-dependent kinases, controls the
expression of numerous cell cycle genes. A cyclic AMP-responsive element (CRE), located …

Allosteric modulators of class-C G-protein-coupled receptors open new possibilities for therapeutic application

C Goudet, V Binet, L Prezeau, JP Pin - Drug Discovery Today: Therapeutic …, 2004 - Elsevier
The two main neurotransmitters, glutamate and GABA, as well as calcium ions, sweet taste
molecules and some pheromones, act on class-C G-protein-coupled receptors (GPCRs). …

Du mécanisme d'activation des domaines heptahélices du récepteur GABAB

V Binet - 2005 - theses.fr
Le récepteur GABAB est un acteur de la neurotransmission. Sa position de cible thérapeutique
motive son étude. C'est un récepteur de la grande famille des récepteurs couplés aux …

[HTML][HTML] Généalogie de Alfred BINET

J Baptiste, F Antoine, J Virginie, EJ Baptiste… - geneastar.org
Alfred Edouard Louis Antoine Binet (Alfredo Binetti), né le 8 juillet 1857 à Nice (alors dans la
division de Nice du royaume de Sardaigne) et mort le 18 octobre 1911 à Paris (14e), est un …

[CITATION][C] Généralisation des analyses salivaires dans un contexte routier: difficultés rencontrées depuis 5 ans, synthèse des résultats d'une enquête réalisée en …

…, T Willeman, J Bourgine, M Loilier, V Binet… - … Analytique Et Clinique, 2022 - Elsevier