Molecular biology and pharmacology of cloned opioid receptors1

…, L Fang, JY Wang, VJ Hruby, WR Roeske… - The FASEB …, 1995 - Wiley Online Library
The cloning and expression of DNA for the three major opioid receptor types (μ, δ, and χ)
present new research opportunities for the characterization of opioid drugs and their …

The δ-opioid receptor: molecular pharmacology, signal transduction, and the determination of drug efficacy

…, SM Cowell, CA Slate, FJ Ehlert, WR Roeske… - Pharmacological …, 1999 - ASPET
Although it was long thought that opioid drugs act on specific receptor sites, opioid receptors
themselves were not identified until about 25 years ago (Pert and Snyder, 1973; Simon et al.…

SR141716A is an inverse agonist at the human cannabinoid CB1 receptor

…, TH Burkey, P Consroe, WR Roeske… - European journal of …, 1997 - Elsevier
… Author links open overlay panel Robert S Landsman a b c d e , Thomas H Burkey a b c d
e , Paul Consroe a b c d e , William R Roeske a b c d e , Henry I Yamamura a b c d e …

Noninvasive evaluation of ventricular hypertrophy in professional athletes.

WR Roeske, RA O'Rourke, A Klein, G Leopold… - Circulation, 1976 - Am Heart Assoc
Athletes often exhibit ECG findings which are considered to be abnormal. Therefore, we
used noninvasive graphic methods to study 42 active professional male basketball players, …

Systemic toxic effects associated with high-dose verapamil infusion and chemotherapy administration

GD Pennock, WS Dalton, WR Roeske… - JNCI: Journal of the …, 1991 - academic.oup.com
Aside from its more conventional uses as a cardiovascular drug, the calcium channel
blocker verapamil has recently been added to chemotherapeutic regimens to reduce drug …

The cloning and expression of a human creatine transporter

…, R Horvath, M Nguyen, S Waite, WR Roeske… - Biochemical and …, 1994 - Elsevier
A human creatine transporter (hCRT-BS2M) cDNA clone was isolated from a human
brainstem/spinal cord using a PCR and phage plaque hybridization based technique. This clone …

[PDF][PDF] Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization.

JZ Fields, WR Roeske, E Morkin… - Journal of Biological …, 1978 - researchgate.net
The parasympathetic nervous system modulates heart rate and myocardial contractility. We
have labeled the parasympathetic muscarinic cholinergic receptors in rabbit, rat, and guinea …

Agonist-specific regulation of the δ-opioid receptor

…, E Navratilova, D Stropova, J Jambrosic, WR Roeske… - Life sciences, 2004 - Elsevier
Delta opioid receptor (DOR) agonists are attractive potential analgesics, since these compounds
exhibit strong antinociceptive activity with relatively few side effects. In the past decade, …

Identification of a human delta opioid receptor: cloning and expression

…, G Santoro, EV Varga, VJ Hruby, WR Roeske… - Life sciences, 1994 - Elsevier
The δ opioid receptor is an important target for analgesic drug development. This report
describes the identification of δ opioid receptor clones from human cDNA libraries and the …

Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain

…, P Consroe, FJ Ehlert, Y Hosohata, WR Roeske… - European journal of …, 1997 - Elsevier
We measured (−)-5-(1,1-dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-phenol
(CP 55,940)-, (−)11-OH-Δ 8 -tetrahydrocannabinol-dimethylheptyl (HU-210)-, anandamide- …