The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress
SM Smith, WW Vale - Dialogues in clinical neuroscience, 2006 - Taylor & Francis
Animals respond to stress by activating a wide array of behavioral and physiological responses
that are collectively referred to as the stress response. Corticotropin-releasing factor (…
that are collectively referred to as the stress response. Corticotropin-releasing factor (…
CRF and CRF receptors: role in stress responsivity and other behaviors
TL Bale, WW Vale - Annu. Rev. Pharmacol. Toxicol., 2004 - annualreviews.org
Since corticotropin-releasing factor (CRF) was first characterized, a growing family of ligands
and receptors has evolved. The mammalian family members include CRF, urocortinI (UcnI), …
and receptors has evolved. The mammalian family members include CRF, urocortinI (UcnI), …
The neurobiology of depression: inroads to treatment and new drug discovery
CB Nemeroff, WW Vale - Journal of Clinical Psychiatry, 2005 - psychiatrist.com
… Vale has received grant/research support from the National Institutes of Health, Kleberg …
Bale TL, Vale WW. CRF and CRF receptors: role in stress responsivity and other behaviors. …
Bale TL, Vale WW. CRF and CRF receptors: role in stress responsivity and other behaviors. …
Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing
…, LW Swanson, PE Sawchenko, J Rivier, WW Vale… - Nature, 1983 - nature.com
Alternative processing of the RNA transcribed from the calcitonin gene appears to result in the
production of a messenger RNA in neural tissue distinct from that in thyroidal ‘C’ cells. The …
production of a messenger RNA in neural tissue distinct from that in thyroidal ‘C’ cells. The …
Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study
LW Swanson, PE Sawchenko, J Rivier, WW Vale - Neuroendocrinology, 1983 - karger.com
… Since antiserum 24 has been found to interн act with rat CRF particularly well in
radioimmunoassays [Vale, unн published observations], it was used extensively for the mapping …
radioimmunoassays [Vale, unн published observations], it was used extensively for the mapping …
Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor
…, J Rivier, PE Sawchenko, WW Vale - Proceedings of the …, 2001 - National Acad Sciences
The corticotropin-releasing factor (CRF) family of neuropeptides includes the mammalian
peptides CRF, urocortin, and urocortin II, as well as piscine urotensin I and frog sauvagine. The …
peptides CRF, urocortin, and urocortin II, as well as piscine urotensin I and frog sauvagine. The …
Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors
…, J Gulyas, J Rivier, WW Vale… - Proceedings of the …, 2001 - National Acad Sciences
Here we describe the cloning and initial characterization of a previously unidentified CRF-related
neuropeptide, urocortin II (Ucn II). Searches of the public human genome database …
neuropeptide, urocortin II (Ucn II). Searches of the public human genome database …
Expression cloning of a human corticotropin-releasing-factor receptor.
…, KA Lewis, MH Perrin, WW Vale - Proceedings of the …, 1993 - National Acad Sciences
Corticotropin-releasing factor (CRF) is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical
axis and plays an important role in coordinating the endocrine, autonomic…
axis and plays an important role in coordinating the endocrine, autonomic…
Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress
…, LH Gold, PE Sawchenko, GF Koob, WW Vale… - Nature …, 2000 - nature.com
Corticotropin-releasing hormone (Crh) is a critical coordinator of the hypothalamic-pituitary-adrenal
(HPA) axis. In response to stress, Crh released from the paraventricular nucleus (…
(HPA) axis. In response to stress, Crh released from the paraventricular nucleus (…
Expression cloning of an activin receptor, a predicted transmembrane serine kinase
LS Mathews, WW Vale - Cell, 1991 - cell.com
Activins are involved in the regulation of multiple biological events, ranging from early
development to pituitary function. To characterize the cellular mechanisms involved in these …
development to pituitary function. To characterize the cellular mechanisms involved in these …