Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-κB pathways and inhibition of intracellular ROS/RNS …
…, PF Wu, F Wang, Z Xiong, YJ Yang, WN Wu… - Free Radical Biology …, 2009 - Elsevier
Many natural polyphenolic compounds have been shown to attenuate reactive oxygen/nitrogen
species (ROS/RNS) formation and protect against ischemia/reperfusion injury both in …
species (ROS/RNS) formation and protect against ischemia/reperfusion injury both in …
[HTML][HTML] NLRP1 inflammasome contributes to chronic stress-induced depressive-like behaviors in mice
…, YJ Zhu, J Zhou, YL Wang, LZ Xu, WN Wu - Journal of …, 2020 - Springer
Background Major depressive disorder (MDD) is a highly prevalent psychiatric disorder, and
inflammation has been considered crucial components of the pathogenesis of depression. …
inflammation has been considered crucial components of the pathogenesis of depression. …
Existence and distinction of acid‐evoked currents in rat astrocytes
C Huang, Z Hu, WN Wu, DF Yu, QJ Xiong, JR Song… - Glia, 2010 - Wiley Online Library
Astrocytes are vital structures that support and/or protect neighboring neurons from pathology.
Although it is generally accepted that glutamate receptors mediate most astrocyte effects, …
Although it is generally accepted that glutamate receptors mediate most astrocyte effects, …
Hyperoside protects cortical neurons from oxygen–glucose deprivation–reperfusion induced injury via nitric oxide signal pathway
RL Liu, QJ Xiong, Q Shu, WN Wu, J Cheng, H Fu… - Brain research, 2012 - Elsevier
Hyperoside is a flavonoid compound and widely used in clinic to relieve pain and improve
cardiovascular functions. However, the effects of hyperoside on ischemic neurons and the …
cardiovascular functions. However, the effects of hyperoside on ischemic neurons and the …
Acid-sensing ion channels contribute to the effect of acidosis on the function of dendritic cells
J Tong, WN Wu, X Kong, PF Wu, L Tian… - The Journal of …, 2011 - journals.aai.org
As an H+-gated subgroup of the degenerin/epithelial Na+ channel family, acid-sensing ion
channels (ASICs) were reported to be involved in various physiological and pathological …
channels (ASICs) were reported to be involved in various physiological and pathological …
Sinomenine protects against ischaemic brain injury: Involvement of co‐inhibition of acid‐sensing ion channel 1a and L‐type calcium channels
WN Wu, PF Wu, XL Chen, Z Zhang, J Gu… - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE Sinomenine (SN), a bioactive alkaloid, has been utilized
clinically to treat rheumatoid arthritis in China. Our preliminary experiments indicated that it …
clinically to treat rheumatoid arthritis in China. Our preliminary experiments indicated that it …
[HTML][HTML] Sinomenine exerts anticonvulsant profile and neuroprotective activity in pentylenetetrazole kindled rats: involvement of inhibition of NLRP1 inflammasome
B Gao, Y Wu, YJ Yang, WZ Li, K Dong, J Zhou… - Journal of …, 2018 - Springer
Background Epilepsy is a common neurological disorder and is not well controlled by
available antiepileptic drugs (AEDs). Inflammation is considered to be a critical factor in the …
available antiepileptic drugs (AEDs). Inflammation is considered to be a critical factor in the …
Exploring the determinants of viewers' loyalty toward beauty YouTubers: a parasocial interaction perspective
HC Ko, WN Wu - Proceedings of the 1st International Conference on …, 2017 - dl.acm.org
Managing a YouTube channel has become a key strategy for YouTubers to establish personal
branding. Popular YouTubers even have the opportunities to work with businesses and …
branding. Popular YouTubers even have the opportunities to work with businesses and …
Acid-sensing ion channels contribute to the effect of extracellular acidosis on proliferation and migration of A549 cells
Y Wu, B Gao, QJ Xiong, YC Wang, DK Huang… - Tumor …, 2017 - journals.sagepub.com
Acid-sensing ion channels, a proton-gated cation channel, can be activated by low extracellular
pH and involved in pathogenesis of some tumors such as glioma and breast cancer. …
pH and involved in pathogenesis of some tumors such as glioma and breast cancer. …
[HTML][HTML] Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons
…, Y Wu, YY Yin, LY Dong, ZW Chen, WN Wu - Journal of …, 2015 - Springer
Background Acid-sensing ion channels (ASICs) are cation channels which were activated by
extracellular acidosis and involved in various physiological and pathological processes in …
extracellular acidosis and involved in various physiological and pathological processes in …