General considerations on rapid desensitization for drug hypersensitivity–a consensus statement
…, P Campi, ML Sanz, M Castells, P Demoly, WJ Pichler… - Allergy, 2010 - Wiley Online Library
To cite this article: Cernadas JR, Brockow K, Romano A, Aberer W, Torres MJ, Bircher A, Campi
P, Sanz ML, Castells M, Demoly P, Pichler WJ, for the European Network of Drug Allergy …
P, Sanz ML, Castells M, Demoly P, Pichler WJ, for the European Network of Drug Allergy …
Skin testing in patients with hypersensitivity reactions to iodinated contrast media–a European multicenter study
…, P Bonadonna, E Faria, G Kanny, M Lerch, WJ Pichler… - Allergy, 2009 - Wiley Online Library
Background: Iodinated contrast media cause both immediate and nonimmediate
hypersensitivity reactions. The aim of this prospective study was to determine the specificity and …
hypersensitivity reactions. The aim of this prospective study was to determine the specificity and …
Adverse side‐effects to biological agents
WJ Pichler - Allergy, 2006 - Wiley Online Library
Biological agents‐like cytokines, monoclonal antibodies and fusion proteins are widely used
in anti‐inflammatory and tumour therapy. They are highly efficient in certain diseases, but …
in anti‐inflammatory and tumour therapy. They are highly efficient in certain diseases, but …
Delayed drug hypersensitivity reactions–new concepts
SJ Posadas, WJ Pichler - Clinical & Experimental Allergy, 2007 - Wiley Online Library
Immune reactions to small molecular compounds such as drugs can cause a variety of
diseases mainly involving skin, but also liver, kidney, lungs and other organs. In addition to the …
diseases mainly involving skin, but also liver, kidney, lungs and other organs. In addition to the …
Allopurinol hypersensitivity is primarily mediated by dose‐dependent oxypurinol‐specific T cell response
…, S Fontana, CR Largiadèr, WJ Pichler… - Clinical & …, 2013 - Wiley Online Library
Background Allopurinol is a main cause of severe cutaneous adverse reactions ( SCAR ).
How allopurinol induces hypersensitivity remains unknown. Pre‐disposing factors are the …
How allopurinol induces hypersensitivity remains unknown. Pre‐disposing factors are the …
In vitro drug causality assessment in Stevens–Johnson syndrome – alternatives for lymphocyte transformation test
…, M Bosak, TT Kawabata, WJ Pichler - Clinical & …, 2013 - Wiley Online Library
Background Patients with Stevens–Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN)
are often exposed simultaneously to a few potentially culprit drugs. However, both the …
are often exposed simultaneously to a few potentially culprit drugs. However, both the …
[HTML][HTML] Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation
…, A Keogh, D Inderbitzin, D Candinas, WJ Pichler - American journal of …, 2009 - Elsevier
DRESS syndrome (drug rash with eosinophilia and systemic symptoms) is a rare drug
hypersensitivity reaction with a significant mortality. We describe a 60-year-old man with …
hypersensitivity reaction with a significant mortality. We describe a 60-year-old man with …
CD69 upregulation on T cells as an in vitro marker for delayed‐type drug hypersensitivity
…, L Zaccaria, T Kawabata, BO Gerber, WJ Pichler - Allergy, 2008 - Wiley Online Library
Background: T cells play a key role in delayed‐type drug hypersensitivity reactions. Their
reactivity can be assessed by their proliferation in response to the drug in the lymphocyte …
reactivity can be assessed by their proliferation in response to the drug in the lymphocyte …
In vitro diagnosis of T cell‐mediated drug allergy
…, A Gschwend‐Zawodniak, WJ Pichler - Clinical & …, 2011 - Wiley Online Library
Cite this as: G. Porebski, A. Gschwend‐Zawodniak and WJ Pichler, Clinical & Experimental
Allergy, 2011 (41) 461–470. Summary Diagnosis of drug hypersensitivity relies on history, …
Allergy, 2011 (41) 461–470. Summary Diagnosis of drug hypersensitivity relies on history, …
T cell‐mediated hypersensitivity to quinolones: mechanisms and cross‐reactivity
…, JPH Depta, WJ Pichler - Clinical & Experimental …, 2006 - Wiley Online Library
Background Quinolones are widely used, broad spectrum antibiotics that can induce immediate‐
and delayed‐type hypersensitivity reactions, presumably either IgE or T cell mediated, …
and delayed‐type hypersensitivity reactions, presumably either IgE or T cell mediated, …