Benzamide-type AMPA receptor modulators form two subfamilies with distinct modes of action

AC Arai, YF Xia, G Rogers, G Lynch… - Journal of Pharmacology …, 2002 - ASPET
CX516 (BDP-12) and CX546, two first-generation benzamide-type AMPA receptor modulators,
were compared with regard to their influence on AMPA receptor-mediated currents, …

MeCP2 in cholinergic interneurons of nucleus accumbens regulates fear learning

Y Zhang, Y Zhu, SX Cao, P Sun, JM Yang, YF Xia… - Elife, 2020 - elifesciences.org
Methyl-CpG-binding protein 2 (MeCP2) encoded by the MECP2 gene is a transcriptional
regulator whose mutations cause Rett syndrome (RTT). Mecp2-deficient mice show fear …

Cancer Metastasis–Suppressing Peptide Metastin Upregulates Excitatory Synaptic Transmission in Hippocampal Dentate Granule Cells

AC Arai, YF Xia, E Suzuki, M Kessler… - Journal of …, 2005 - journals.physiology.org
Metastin is an antimetastatic peptide encoded by the KiSS-1 gene in cancer cells. Recent
studies found that metastin is a ligand for the orphan G-protein–coupled receptor GPR54, …

Neural representation of sound duration in the inferior colliculus of the mouse

YF Xia, ZH Qi, JX Shen - Acta oto-laryngologica, 2000 - Taylor & Francis
In this study we examined the neuronal responses of single units to different sound durations
in the inferior colliculus (IC) of the mouse. One hundred and one recorded units were …

Positive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor modulators have different impact on synaptic transmission in the thalamus and …

YF Xia, M Kessler, AC Arai - Journal of Pharmacology and Experimental …, 2005 - ASPET
Earlier studies showed that positive modulators of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic
acid (AMPA) receptors enhance synaptic responses and facilitate synaptic plasticity…

[HTML][HTML] Acute amphetamine exposure selectively desensitizes κ-opioid receptors in the nucleus accumbens

Y Xia, L He, JL Whistler, GO Hjelmstad - Neuropsychopharmacology, 2008 - nature.com
In the present study, we investigated the effects of psychostimulant exposure on κ-opioid
peptide (KOP) receptor signaling in the rat mesolimbic system. A single subcutaneous (sc) …

Substance P inhibits GABAB receptor signalling in the ventral tegmental area

YF Xia, EB Margolis, GO Hjelmstad - The Journal of physiology, 2010 - Wiley Online Library
Substance P (SP) and its receptors are involved in anxiety‐related behaviours and regulate
the intake of drugs of abuse and alcohol. Within the midbrain ventral tegmental area (VTA), a …

Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4

…, W Huang, YY Shugart, MK Lee, F Zhang, JC Xia… - Nature …, 2002 - nature.com
Nasopharyngeal carcinoma (NPC) occurs with high frequency in Asian populations,
especially among people of Cantonese ancestry. In areas with high incidence, NPC clusters in …

Effects of 5′-alkyl-benzothiadiazides on (R, S)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor biophysics and synaptic responses

AC Arai, YF Xia, M Kessler, D Phillips… - Molecular …, 2002 - ASPET
Alkyl-substituted benzothiadiazides (BTDs) were tested for their effects on (R,S)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic
acid (AMPA)-type glutamate receptors. In excised …

Increased Ca2+ influx through Na+/Ca2+ exchanger during long‐term facilitation at crayfish neuromuscular junctions

A Minami, Y Xia, RS Zucker - The Journal of physiology, 2007 - Wiley Online Library
Intense motor neuron activity induces a long‐term facilitation (LTF) of synaptic transmission
at crayfish neuromuscular junctions (NMJs) that is accompanied by an increase in the …