Cross-talk between SOX2 and TGFβ signaling regulates EGFR–TKI tolerance and lung cancer dissemination
These findings suggest the potential of SOX2 as a prognostic marker in EGFR-mutant lung
cancer, as SOX2-mediated cell plasticity regulated by TGFβ stimulation and epigenetic …
cancer, as SOX2-mediated cell plasticity regulated by TGFβ stimulation and epigenetic …
Down-regulation of Rad51 expression overcomes drug resistance to gemcitabine in human Non–Small-Cell Lung cancer cells
MS Tsai, YH Kuo, YF Chiu, YC Su, YW Lin - Journal of Pharmacology and …, 2010 - ASPET
Gemcitabine (2′,2′-difluorodeoxycytidine), a deoxycytidine analog, and erlotinib, an
epidermal growth factor receptor-tyrosine kinase inhibitor, are used clinically to treat patients with …
epidermal growth factor receptor-tyrosine kinase inhibitor, are used clinically to treat patients with …
Expression of neuroendocrine factor VGF in lung cancer cells confers resistance to EGFR kinase inhibitors and triggers epithelial-to-mesenchymal transition
W Hwang, YF Chiu, MH Kuo, KL Lee, AC Lee, CC Yu… - Cancer research, 2017 - AACR
Mutations in EGFR drive tumor growth but render tumor cells sensitive to treatment with
EGFR tyrosine kinase inhibitors (TKI). Phenotypic alteration in epithelial-to-mesenchymal …
EGFR tyrosine kinase inhibitors (TKI). Phenotypic alteration in epithelial-to-mesenchymal …
Fabrication of Ni nanowires for hydrogen evolution reaction in a neutral electrolyte
Hydrogen evolution reaction in 1M Na 2 SO 4 was investigated using Ni nanowires in
diameter of 250nm with exposed lengths of 20, 35, and 45μm, respectively. The Ni nanowires …
diameter of 250nm with exposed lengths of 20, 35, and 45μm, respectively. The Ni nanowires …
Emodin enhances cisplatin-induced cytotoxicity via down-regulation of ERCC1 and inactivation of ERK1/2
…, YJ Su, ST Lin, JY Jhan, SC Ciou, CM Cheng, YF Chiu… - Lung Cancer, 2010 - Elsevier
Emodin, a tyrosine kinase inhibitor, is a natural anthraquinone derivative found in the roots
and rhizomes of numerous plants; it exhibits an anticancer effect on many malignancies. The …
and rhizomes of numerous plants; it exhibits an anticancer effect on many malignancies. The …
[HTML][HTML] Critical role of SOX2–IGF2 signaling in aggressiveness of bladder cancer
YF Chiu, CC Wu, MH Kuo, CC Miao, MY Zheng… - Scientific Reports, 2020 - nature.com
Signaling elicited by the stem cell factors SOX2, OCT4, KLF4, and MYC not only mediates
reprogramming of differentiated cells to pluripotency but has also been correlated with tumor …
reprogramming of differentiated cells to pluripotency but has also been correlated with tumor …
Synergistic effect of curcumin and cisplatin via down-regulation of thymidine phosphorylase and excision repair cross-complementary 1 (ERCC1)
Curcumin (diferuloylmethane), a phenolic compound obtained from the rhizome of Curcuma
longa, is known to have antiproliferative and antitumor properties. Thymidine …
longa, is known to have antiproliferative and antitumor properties. Thymidine …
Role of Rad51 down-regulation and extracellular signal-regulated kinases 1 and 2 inactivation in emodin and mitomycin C-induced synergistic cytotoxicity in human …
YJ Su, MS Tsai, YH Kuo, YF Chiu, CM Cheng… - Molecular …, 2010 - ASPET
Emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone derivative
found in the roots and rhizomes of numerous plants. It is a tyrosine kinase inhibitor and has …
found in the roots and rhizomes of numerous plants. It is a tyrosine kinase inhibitor and has …
Negative-capacitance FinFET inverter, ring oscillator, SRAM cell, and Ft
…, WC Chiu, HC Chen, MH Lee, YF Chiu… - 2018 IEEE …, 2018 - ieeexplore.ieee.org
In this work, we use thermal-ALD to prepare ferroelectric HfZrO 2 (HZO) thin film with thickness
from 3 to 7 nm for the NC-FinFET's gate stack. The subthreshold swing (SS) was as low …
from 3 to 7 nm for the NC-FinFET's gate stack. The subthreshold swing (SS) was as low …
Inhibition of p38 MAPK-dependent excision repair cross-complementing 1 expression decreases the DNA repair capacity to sensitize lung cancer cells to etoposide
Etoposide (VP-16), a topoisomerase II inhibitor, is an effective anticancer drug currently
used for the treatment of a wide range of cancers. Excision repair cross-complementary 1 (…
used for the treatment of a wide range of cancers. Excision repair cross-complementary 1 (…