The ontogeny of presynaptic elements of GABAergic neurons has been studied in the
cerebrum of the chick embryo both in vivo and in vitro. The specific activity of glutamate …

The Ca 2+ -ATPase from rat liver microsomes has been solubilized in Triton X-100 and
purified to homogeneity by ficollsucrose treatment, column chromatography with agarose-hexane …

Dopamine pathway genes have been the subject of a variety of studies testing the association
of candidate genes and liability for attention‐deficit hyperactivity disorder (ADHD). Due to …

Attention-deficit hyperactivity disorder (ADHD) subtypes in DSM-IV are defined by the
presence of 6 or more inattentive and/or the presence of 6 or more hyperactive/impulsive …

Nuclear Ca 2 + plays a critical role in many cellular functions although its mode (s) of regulation
is unclear. This study shows that the metabotropic glutamate receptor, mGlu5, mobilizes …

G-protein-coupled receptors are thought to transmit extracellular signals to the cytoplasm
from their position on the cell surface. Some receptors, including the metabotropic glutamate …

Traditionally, signal transduction from GPCRs is thought to emanate from the cell surface
where receptor interactions with external stimuli can be transformed into a broad range of …

G-protein-coupled receptors are well known for converting an extracellular signal into an
intracellular response. Here we showed that the metabotropic glutamate receptor 5 (mGlu5) …

Oxidative stress is a key player in a variety of neurodegenerative disorders including
Parkinson's disease. Widely used as a parkinsonian mimetic, 6‐hydroxydopamine (6‐OHDA) …

Recently we have shown that the metabotropic glutamate 5 (mGlu5) receptor can be expressed
on nuclear membranes of heterologous cells or endogenously on striatal neurons where …