The new melokhanines A–J (1–10) and 22 known (11–32) alkaloids were isolated from the
twigs and leaves of Melodinus khasianus. The new compounds and their absolute …

Stroke is a leading global cause of mortality and disability. Less than 5% of patients are
able to receive tissue plasminogen activator thrombolysis within the necessary timeframe. …

Ganoderma lingzhi is a valuable, edible and medicinal fungus that has been widely used for
the prevention and treatment of a broad range of diseases. In this study, spirolingzhines A–…

T-type calcium channel (TTCC) inhibitors hold great potential for the treatment of a variety of
neurological disorders. Cochlearoids A–E (1–5), five pairs of dimeric meroterpenoid …

Recent studies focusing on unveiling the biological agents of Aspongopus chinensis have
led to the identification of four new norepinephrine derivatives (1–4), three new …

The failure of past efforts to develop effective stroke treatments is at least partially because
these treatments often interfered with essential physiological functions, even though they are …

(±)-Aspongamide A (1), an unusual trimer of N-acetyldopamine (NADA) bearing a novel
tetrahydrobenzo[a]dibenzo[b,e][1,4]dioxine structure, and a pair of NADA dimeric enantiomers (2…

The bioassay-guided chemical investigation of the stems of Dendrobium fimbriatum Hook led
to the isolation of seven first reported bibenzyl dimers with a linkage of a methylene moiety, …

Salvicine, a structurally modified diterpenoid quinone derived from Salvia prionitis, is a
nonintercalative topoisomerase II (topo II) poison. The compound possesses potent in vitro and in …

Ethnopharmacological relevance Several Ganoderma fungi are well-known for their
medical uses to treat cancer, insomnia and kidney disease in East Asia. Triperpenoids and …