Fast Forward

Molecular Pharmacology Fast Forward contains papers in manuscript form that have been accepted and published in Molecular Pharmacology but have not been copyedited and have not been assigned to an issue of the journal. Copyediting may lead to some differences between the Fast Forward version and the final version. There may also be differences in the quality of the graphics. The publication date appears below each title followed by the article's unique Digital Object Identifier (DOI).

Articles

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A functional NaV1.7-NavAb chimera with a reconstituted high affinity ProTx-II binding site
Ramkumar Rajamani, Sophie Wu, Iyoncy Rodrigo, Mian Gao, Simon Low, Lisa Megson, David Wensel, Rick Pieschl, Debra Post-Munson, John Watson, David R Langley, Michael Ahlijanian, Linda Bristow and James Herrington

Molecular Pharmacology June 23, 2017, mol.117.108712; DOI: https://doi.org/10.1124/mol.117.108712
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Determination of the residues in the extracellular domain of the nicotinic α subunit required for the actions of physostigmine on neuronal nicotinic receptors
Xiaochun Jin, Allison L Germann, Daniel J Shin, Gustav Akk and Joseph H. Steinbach

Molecular Pharmacology June 19, 2017, mol.117.108894; DOI: https://doi.org/10.1124/mol.117.108894
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Pore polarity and charge determine differential block of Kir1.1 and Kir7.1 potassium channels by the small-molecule inhibitor VU590
Sujay Kharade, Jonathan Sheehan, Eric Figueroa, Jens Meiler and Jerod Denton

Molecular Pharmacology June 15, 2017, mol.117.108472; DOI: https://doi.org/10.1124/mol.117.108472
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TCL1A SNPs and estrogen-mediated toll-like receptor-MYD88-dependent NF-κB activation: SNP and SERM-dependent modification of inflammation and immune response
Ming-Fen Ho, James N Ingle, Tim Bongartz, Krishna R Kalari, Paul E Goss, Lois E Shepherd, Taisei Mushiroda, Michiaki Kubo, Liewei Wang and Richard M Weinshilboum

Molecular Pharmacology June 14, 2017, mol.117.108340; DOI: https://doi.org/10.1124/mol.117.108340
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Identification of AICP as a GluN2C-selective NMDA receptor superagonist at the GluN1 glycine site
Maja Jessen, Kristen Frederiksen, Feng Yi, Rasmus P Clausen, Kasper B Hansen, Hans Brauner-Osborne, Paul Kilburn and Anders Damholt

Molecular Pharmacology June 6, 2017, mol.117.108944; DOI: https://doi.org/10.1124/mol.117.108944
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C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways
Jeffrey S Smith, Priya Alagesan, Nimit K Desai, Thomas F Pack, Jiao-Hui Wu, Asuka Inoue, Neil J Freedman and Sudarshan Rajagopal

Molecular Pharmacology May 30, 2017, mol.117.108522; DOI: https://doi.org/10.1124/mol.117.108522
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Direct Binding of the Corrector VX-809 to human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 interface
Rhea P Hudson, Jennifer E Dawson, P. Andrew Chong, Zhengrong Yang, Linda Millen, Philip J. Thomas, Christie G. Brouillette and Julie D. Forman-Kay

Molecular Pharmacology May 25, 2017, mol.117.108373; DOI: https://doi.org/10.1124/mol.117.108373
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Alterations of Histone Modifications Contribute to Pregnane X Receptor-mediated Induction of CYP3A4 by Rifampicin
Liang Yan, Yiting Wang, Jingyang Liu, Yali Nie, Xiaobo Zhong, Quancheng Kan and Lirong Zhang

Molecular Pharmacology May 25, 2017, mol.117.108225; DOI: https://doi.org/10.1124/mol.117.108225
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Statins Attenuate Activation of the NLRP3 Inflammasome by Oxidized-LDL or TNF-α in Vascular Endothelial Cells through a PXR-dependent mechanism
Shaolan Wang, Xinya Xie, Ting Lei, Kang Zhang, Baochang Lai, Zihui Zhang, Youfei Guan, Guangmei Mao, Lei Xiao and Nanping Wang

Molecular Pharmacology May 25, 2017, mol.116.108100; DOI: https://doi.org/10.1124/mol.116.108100
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Alpha 2 subunit-containing GABA_A receptor subtypes are up-regulated and contribute to alcohol-induced functional plasticity in rat hippocampus
A Kerstin Lindemeyer, Yi Shen, Ferin Yazdani, Xuesi M Shao, Igor Spigelman, Daryl L Davies, Richard W Olsen and Jing Liang

Molecular Pharmacology May 23, 2017, mol.116.107797; DOI: https://doi.org/10.1124/mol.116.107797
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β-Arrestin-mediated Regulation of the Human Ether-a-go-go-Related Gene (hERG) Potassium Channel
Matthew G Sangoi, Shawn M Lamothe, Jun Guo, Tonghua Yang, Wentao Li, Ellen G Avery, John T Fisher and Shetuan Zhang

Molecular Pharmacology May 11, 2017, mol.116.108035; DOI: https://doi.org/10.1124/mol.116.108035
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GABABR-Induced EGFR Transactivation Promotes Migration of Human Prostate Cancer Cells
Shuai Xia, Cong He, Yini Zhu, Suyun Wang, Huiping Li, Zhongling Zhang, Xinnong Jiang and Jianfeng Liu

Molecular Pharmacology April 19, 2017, mol.116.107854; DOI: https://doi.org/10.1124/mol.116.107854
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GRK2 mediates arginine vasopressin-induced IL-6 production via NF-kB signaling in neonatal rat cardiac fibroblast
Feifei Xu, Suzhen Sun, Xiaojun Wang, Eran Ni, Lingling Zhao and Weizhong Zhu

Molecular Pharmacology February 13, 2017, mol.116.107698; DOI: https://doi.org/10.1124/mol.116.107698

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MG53, biological function and potential as a therapeutic target
Yan Zhang, Hong-Kun Wu, Fengxiang Lv and Rui-Ping Xiao

Molecular Pharmacology April 21, 2017, mol.117.108241; DOI: https://doi.org/10.1124/mol.117.108241
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Tumor Microenvironment Targeting and Responsive Peptide-based Nanoformulations for Improved Tumor Therapy
Hao Qin, Yanping Ding, Ayeesha Mujeeb, Ying Zhao and Guangjun Nie

Molecular Pharmacology April 18, 2017, mol.116.108084; DOI: https://doi.org/10.1124/mol.116.108084
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Progress of Pharmacological Sciences in China
Jian-Cheng Wang, Yungui Zhu, Lei Wu and Erdan Dong

Molecular Pharmacology April 12, 2017, mol.116.108167; DOI: https://doi.org/10.1124/mol.116.108167
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The Ca2+-permeable cation TRPV3 channel: an emerging pivotal target for itch and skin diseases
Gongxin Wang and Kewei Wang

Molecular Pharmacology April 4, 2017, mol.116.107946; DOI: https://doi.org/10.1124/mol.116.107946
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Clinical applications of circulating tumor cells in pharmacotherapy: challenges and perspectives
Tong Wu, Bin Cheng and Liwu Fu

Molecular Pharmacology March 29, 2017, mol.116.108142; DOI: https://doi.org/10.1124/mol.116.108142
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Phosphorylation of G protein-coupled receptors: from the barcode hypothesis to the flute model
Zhao Yang, Fan Yang, Daolai Zhang, Zhixin Liu, Amy Lin, Chuan Liu, Peng Xiao, Xiao Yu and Jin-Peng Sun

Molecular Pharmacology February 28, 2017, mol.116.107839; DOI: https://doi.org/10.1124/mol.116.107839
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Advances in Hypoxia-mediated Mechanisms in Hepatocellular Carcinoma
Xin Xin Xiong, Xin Yao Qiu, Dian Xing Hu and Xiao Qian Chen

Molecular Pharmacology February 27, 2017, mol.116.107706; DOI: https://doi.org/10.1124/mol.116.107706
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The emerging role of Cables1 in cancer and other diseases
Jia-Rong Huang, Guang-Mou Tan, Yong Li and Zhi Shi

Molecular Pharmacology January 24, 2017, mol.116.107730; DOI: https://doi.org/10.1124/mol.116.107730

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