Fast Forward

Molecular Pharmacology Fast Forward contains papers in manuscript form that have been accepted and published in Molecular Pharmacology but have not been copyedited and have not been assigned to an issue of the journal. Copyediting may lead to some differences between the Fast Forward version and the final version. There may also be differences in the quality of the graphics. The publication date appears below each title followed by the article's unique Digital Object Identifier (DOI).

Articles

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Tyrosine nitration contributes to nitric oxide-stimulated degradation of CYP2B6
Choon-myung Lee, Ross Wilderman, Ji Won Park, T.J. Murphy and Edward T. Morgan

Molecular Pharmacology July 3, 2020, MOLPHARM-AR-2020-000020; DOI: https://doi.org/10.1124/molpharm.120.000020
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Neprilysin controls the synaptic activity of neuropeptides in the intercalated cells of the amygdala
Gabrielle C Gregoriou, Sahil D Patel, Bryony L Winters and Elena E Bagley

Molecular Pharmacology June 30, 2020, mol.119.119370; DOI: https://doi.org/10.1124/mol.119.119370
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Hydroxynorketamine Blocks NMDA Receptor Currents by Binding to Closed Receptors
Jamie A Abbott and Gabriela K. Popescu

Molecular Pharmacology June 29, 2020, mol.120.119784; DOI: https://doi.org/10.1124/mol.120.119784
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Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence
Boying Guo, Alicia Rodriguez-Gabin, Andrea Prota, Tobias Mühlethaler, Nan Zhang, Kenny Ye, Michel O Steinmetz, Susan Band Horwitz, Amos B Smith and Hayley McDaid

Molecular Pharmacology June 26, 2020, mol.119.117457; DOI: https://doi.org/10.1124/mol.119.117457
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Hsp70:CHIP ubiquitinates dysfunctional but not native neuronal NO synthase
Amanda K Davis, Natalie F. McMyn, Miranda Lau, Yoshihiro Morishima and Yoichi Osawa

Molecular Pharmacology June 26, 2020, mol.120.119990; DOI: https://doi.org/10.1124/mol.120.119990
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Small molecule inhibitors confirm ubiquitin-dependent removal of TOP2-DNA covalent complexes
Rebecca Swan, Luke Poh, Ian G Cowell and Caroline A Austin

Molecular Pharmacology June 25, 2020, mol.119.118893; DOI: https://doi.org/10.1124/mol.119.118893
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OATP-mediated hepatic uptake of glucuronide metabolites of androgens
Cindy Yanfei Li, Anshul Gupta, Zsuzsanna Gáborik, Emese Kis and Bhagwat Prasad

Molecular Pharmacology June 25, 2020, mol.120.119891; DOI: https://doi.org/10.1124/mol.120.119891
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Interaction of MDIMP with the voltage-gated calcium channels
Juan A.M. De La Rosa, Maricela GarcÍa-Castañeda, Takuya Nishigaki, Juan Carlos Gómora, Teresa Mancilla-Percino and Guillermo Ávila

Molecular Pharmacology June 25, 2020, mol.120.119982; DOI: https://doi.org/10.1124/mol.120.119982
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Inhibition of TRPA1 by General Anesthetics
Hoai T Ton, Thieu X Phan and Gerard P Ahern

Molecular Pharmacology June 24, 2020, mol.119.118851; DOI: https://doi.org/10.1124/mol.119.118851
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Heteromeric assembly of truncated neuronal Kv7 channels: implications for neurological disease and pharmacotherapy
Jingru Li, Jasmine Maghera, Shawn M. Lamothe, Elysa J. Marco and Harley T. Kurata

Molecular Pharmacology June 24, 2020, mol.120.119644; DOI: https://doi.org/10.1124/mol.120.119644
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A Methyl Scan of the Pyrrolidinium Ring of Nicotine Reveals Significant Differences in its Interactions with α7 and α4β2 Nicotinic Acetylcholine Receptors
Hong Xing, Kristin W Andrud, Ferenc Soti, Anne Rouchaud, Stephan C Jahn, Ziang Lu, Yeh-hyon Cho, Sophia Habibi, Patrick Corsino, Svetoslav Slavov, James R Rocca, Jon S Lindstrom, Ron J Lukas and William Kem

Molecular Pharmacology May 30, 2020, mol.119.118786; DOI: https://doi.org/10.1124/mol.119.118786
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The phosphodiesterase inhibitor IBMX blocks the potassium channel THIK-1 from the extracellular side
Xinle Zou, Linus J. Conrad, Kristin Koschinski, Günter Schlichthörl, Regina Preisig-Müller, Eugen Netz, Jens Krüger, Jürgen Daut and Vijay Renigunta

Molecular Pharmacology May 28, 2020, MOLPHARM-AR-2020-000011; DOI: https://doi.org/10.1124/molpharm.120.000011
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Chronic treatment with morphine disrupts acute kinase-dependent desensitization of GPCRs
Emily R Leff, Seksiri Arttamangkul and John T Williams

Molecular Pharmacology May 3, 2020, mol.119.119362; DOI: https://doi.org/10.1124/mol.119.119362
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Fentanyl-induced block of hERG channels is exacerbated by hypoxia, hypokalemia, alkalosis, and the presence of hERG1b
Jared N. Tschirhart and Shetuan Zhang

Molecular Pharmacology April 22, 2020, mol.119.119271; DOI: https://doi.org/10.1124/mol.119.119271

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Regulators of G protein signaling in analgesia and addiction
Farhana Sakloth, Claire Polizu, Feodora Bertherat and Venetia Zachariou

Molecular Pharmacology May 30, 2020, mol.119.119206; DOI: https://doi.org/10.1124/mol.119.119206
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Targeting ACE2/Angiotensin-(1-7)/Mas Receptor Axis in the Vascular Progenitor Cells for Cardiovascular Diseases
Yagna PR Jarajapu

Molecular Pharmacology April 22, 2020, mol.119.117580; DOI: https://doi.org/10.1124/mol.119.117580
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Opioid pharmacology under the microscope
Damien Jullié, Arisbel B Gondin, Mark E Von Zastrow and Meritxell Canals

Molecular Pharmacology April 10, 2020, mol.119.119321; DOI: https://doi.org/10.1124/mol.119.119321
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Phosphoproteomic Identification of Vasopressin/cAMP/PKA-Dependent Signaling in Kidney
Karim Salhadar, Allanah Matthews, Viswanathan Raghuram, Kavee Limbutara, Chin-Rang Yang, Arnab Datta, Chung-Lin Chou and Mark A. Knepper

Molecular Pharmacology April 3, 2020, mol.120.119602; DOI: https://doi.org/10.1124/mol.120.119602
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A concise review of concepts in opioid pharmacology up to the discovery of endogenous opioids
Brian M. Cox

Molecular Pharmacology March 31, 2020, mol.120.119420; DOI: https://doi.org/10.1124/mol.120.119420
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Recent progress in opioid research from an electrophysiological perspective
William T Birdsong and John T. Williams

Molecular Pharmacology March 20, 2020, mol.119.119040; DOI: https://doi.org/10.1124/mol.119.119040
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Bidirectional relationship between opioids and disrupted sleep: putative mechanisms
D. Eacret, S. C. Veasey and J. A. Blendy

Molecular Pharmacology March 20, 2020, mol.119.119107; DOI: https://doi.org/10.1124/mol.119.119107
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Defining a cellular map of cAMP nanodomains
Katharina Schleicher and Manuela Zaccolo

Molecular Pharmacology February 28, 2020, mol.119.118869; DOI: https://doi.org/10.1124/mol.119.118869
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RGS proteins as critical regulators of motor function and their implications in Parkinson's disease
Katelin E Ahlers-Dannen, Mackenzie M. Spicer and Rory A. Fisher

Molecular Pharmacology February 3, 2020, mol.119.118836; DOI: https://doi.org/10.1124/mol.119.118836

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