Table of Contents

Articles

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  Effects of Sarcomere Activators and Inhibitors Targeting Myosin Cross-Bridges on Ca²⁺-Activation of Mature and Immature Mouse Cardiac Myofilaments

  Monika Halas, Paulina Langa, Chad M. Warren, Paul H. Goldspink, Beata M. Wolska and R. John Solaro

  Molecular Pharmacology May 2022, 101 (5) 286-299; DOI: https://doi.org/10.1124/molpharm.121.000420
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  Agonist-Specific Regulation of G Protein–Coupled Receptors after Chronic Opioid Treatment

  Sweta Adhikary, Omar Koita, Joseph J. Lebowitz, William T. Birdsong and John T. Williams

  Molecular Pharmacology May 2022, 101 (5) 300-308; DOI: https://doi.org/10.1124/molpharm.121.000453
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  Serotonin-Mediated Activation of Serotonin Receptor Type 1 Oppositely Modulates Voltage-Gated Calcium Channel Currents in Rat Sensory Neurons Innervating Hindlimb Muscle

  Laura Anselmi, Joyce S. Kim, Marc P. Kaufman, Shouhao Zhou and Victor Ruiz-Velasco

  Molecular Pharmacology May 2022, 101 (5) 309-321; DOI: https://doi.org/10.1124/molpharm.121.000419
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  Nuclear Ceramide Is Associated with Ataxia Telangiectasia Mutated Activation in the Neocarzinostatin-Induced Apoptosis of Lymphoblastoid Cells

  Jun Fujita, Makoto Taniguchi, Chieko Hashizume, Yoshibumi Ueda, Shota Sakai, Tadakazu Kondo, Mayumi Hashimoto-Nishimura, Kentaro Hanada, Takeo Kosaka and Toshiro Okazaki

  Molecular Pharmacology May 2022, 101 (5) 322-333; DOI: https://doi.org/10.1124/molpharm.121.000379
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  Live Tissue Imaging Reveals Distinct Transcellular Pathways for Organic Cations and Anions at the Blood-Cerebrospinal Fluid Barrier

  Tao Hu, Weibin Zha, Austin Sun and Joanne Wang

  Molecular Pharmacology May 2022, 101 (5) 334-342; DOI: https://doi.org/10.1124/molpharm.121.000439
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  Influence of the TARP γ8-Selective Negative Allosteric Modulator JNJ-55511118 on AMPA Receptor Gating and Channel Conductance

  Ian D. Coombs, Craig A. Sexton, Stuart G. Cull-Candy and Mark Farrant

  Molecular Pharmacology May 2022, 101 (5) 343-356; DOI: https://doi.org/10.1124/molpharm.121.000473
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  VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels

  Samantha J. McClenahan, Caitlin N. Kent, Sujay V. Kharade, Elena Isaeva, Jade C. Williams, Changho Han, Andrew Terker, Robert Gresham, Roman M. Lazarenko, Emily L. Days, Ian M. Romaine, Joshua A. Bauer, Olivier Boutaud, Gary A. Sulikowski, Raymond Harris, C. David Weaver, Alexander Staruschenko, Craig W. Lindsley and Jerod S. Denton

  Molecular Pharmacology May 2022, 101 (5) 357-370; DOI: https://doi.org/10.1124/molpharm.121.000464
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  The Synthetic Cannabinoid WIN55,212-2 Can Disrupt the Golgi Apparatus Independent of Cannabinoid Receptor-1

  Joshua Lott, Emily M. Jutkiewicz and Manojkumar A. Puthenveedu

  Molecular Pharmacology May 2022, 101 (5) 371-380; DOI: https://doi.org/10.1124/molpharm.121.000377