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Abstract

Common features in the interaction of tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives with the human immunodeficiency virus type 1 reverse transcriptase.

Z Debyser, R Pauwels, M Baba, J Desmyter and E De Clercq
Molecular Pharmacology May 1992, 41 (5) 963-968;

Article Information

vol. 41 no. 5 963-968
PubMed 
1375320
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Published online May 1, 1992.

Author Information

  1. Z Debyser,
  2. R Pauwels,
  3. M Baba,
  4. J Desmyter and
  5. E De Clercq
  1. Rega Institute for Medical Research, Catholic University of Leuven, Belgium.

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    Abstract

    Common features in the interaction of tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives with the human immunodeficiency virus type 1 reverse transcriptase.

    Z Debyser, R Pauwels, M Baba, J Desmyter and E De Clercq
    Molecular Pharmacology May 1, 1992, 41 (5) 963-968;
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