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Research ArticleArticle

The Nicotinic Allosteric Potentiating Ligand Galantamine Facilitates Synaptic Transmission in the Mammalian Central Nervous System

Máriton D. Santos, Manickavasagom Alkondon, Edna F. R. Pereira, Yasco Aracava, Howard M. Eisenberg, Alfred Maelicke and Edson X. Albuquerque
Molecular Pharmacology May 2002, 61 (5) 1222-1234; DOI: https://doi.org/10.1124/mol.61.5.1222

Article Information

vol. 61 no. 5 1222-1234
DOI 
https://doi.org/10.1124/mol.61.5.1222
PubMed 
11961141
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received June 25, 2001
  • Accepted February 4, 2002
  • Published online May 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Máriton D. Santos1,4,
  2. Manickavasagom Alkondon1,
  3. Edna F. R. Pereira1,
  4. Yasco Aracava3,
  5. Howard M. Eisenberg2,
  6. Alfred Maelicke1,5, and
  7. Edson X. Albuquerque1,3
  1. 1Department of Pharmacology and Experimental Therapeutics (M.D.S., M.A., E.F.R.P., A.M., E.X.A.) and 2Department of Neurosurgery (H.M.E.), University of Maryland School of Medicine, Baltimore, Maryland; 3Departmento de Farmacologia Básica e Clı́nica, Instituto de Ciênicas Biomédicas (Y.A., E.X.A.) and 4Instituto de Biofı́sica Carlos Chagas Filho (M.D.S.), Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; and 5Institute of Physiological Chemistry and Pathobiochemistry, Johannes-Gutenberg University Medical School, Duesbergweg, Mainz, Germany (A.M.)
  1. Dr. Edson X. Albuquerque, Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201. E-mail: ealbuque{at}umaryland.edu
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Research ArticleArticle

The Nicotinic Allosteric Potentiating Ligand Galantamine Facilitates Synaptic Transmission in the Mammalian Central Nervous System

Máriton D. Santos, Manickavasagom Alkondon, Edna F. R. Pereira, Yasco Aracava, Howard M. Eisenberg, Alfred Maelicke and Edson X. Albuquerque
Molecular Pharmacology May 1, 2002, 61 (5) 1222-1234; DOI: https://doi.org/10.1124/mol.61.5.1222
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