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Research ArticleArticle

Conformational Constraining of Inactive and Active States of a Seven Transmembrane Receptor by Metal Ion Site Engineering in the Extracellular End of Transmembrane Segment V

Mette M. Rosenkilde, Ralf David, Ilka Oerlecke, Tau Benned-Jensen, Ulf Geumann, Anette G. Beck-Sickinger and Thue W. Schwartz
Molecular Pharmacology December 2006, 70 (6) 1892-1901; DOI: https://doi.org/10.1124/mol.106.027425

Article Information

vol. 70 no. 6 1892-1901
DOI 
https://doi.org/10.1124/mol.106.027425
PubMed 
16971553
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received June 1, 2006
  • Accepted September 12, 2006
  • Published online November 16, 2006.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Mette M. Rosenkilde,
  2. Ralf David,
  3. Ilka Oerlecke,
  4. Tau Benned-Jensen,
  5. Ulf Geumann,
  6. Anette G. Beck-Sickinger and
  7. Thue W. Schwartz
  1. Laboratory for Molecular Pharmacology, Department of Pharmacology, the Panum Institute; University of Copenhagen, Denmark (M.M.R., I.O., T.B-J., T.W.S); and Institute of Biochemistry, Faculty of Biosciences, Pharmacy and Psychology, University of Leipzig, Leipzig, Germany (R.D., U.G., A.G.B-S).
  1. Address correspondence to:
    Mette M. Rosenkilde, Laboratory for Molecular Pharmacology, Department of Pharmacology, The Panum Institute 18.6, Bleg-damsvej 3, 2200 Copenhagen N, Denmark. E-mail: rosenkilde{at}molpharm.dk.
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Research ArticleArticle

Conformational Constraining of Inactive and Active States of a Seven Transmembrane Receptor by Metal Ion Site Engineering in the Extracellular End of Transmembrane Segment V

Mette M. Rosenkilde, Ralf David, Ilka Oerlecke, Tau Benned-Jensen, Ulf Geumann, Anette G. Beck-Sickinger and Thue W. Schwartz
Molecular Pharmacology December 1, 2006, 70 (6) 1892-1901; DOI: https://doi.org/10.1124/mol.106.027425
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