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Research ArticleArticle

Loss of the High-Affinity Pentamidine Transporter Is Responsible for High Levels of Cross-Resistance between Arsenical and Diamidine Drugs in African Trypanosomes

Daniel J. Bridges, Matthew K. Gould, Barbara Nerima, Pascal Mäser, Richard J. S. Burchmore and Harry P. de Koning
Molecular Pharmacology April 2007, 71 (4) 1098-1108; DOI: https://doi.org/10.1124/mol.106.031351

Article Information

vol. 71 no. 4 1098-1108
DOI 
https://doi.org/10.1124/mol.106.031351
PubMed 
17234896
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received October 2, 2006
  • Accepted January 16, 2007
  • Published online March 21, 2007.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Daniel J. Bridges,
  2. Matthew K. Gould,
  3. Barbara Nerima,
  4. Pascal Mäser,
  5. Richard J. S. Burchmore and
  6. Harry P. de Koning
  1. Institute of Biomedical and Life Sciences, Division of Infection and Immunity, University of Glasgow, Glasgow, UK (D.J.B., M.K.G., R.J.S.B., H.P.d.K.), and Institute of Cell Biology, University of Bern, Switzerland (B.N., P.M.)
  1. Address correspondence to:
    Dr. Harry P. de Koning, Institute of Biomedical and Life Sciences, Glasgow Biomedical Research Centre, University of Glasgow, Glasgow G12 8TA, United Kingdom. E-mail: h.de-koning{at}bio.gla.ac.uk
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Research ArticleArticle

Loss of the High-Affinity Pentamidine Transporter Is Responsible for High Levels of Cross-Resistance between Arsenical and Diamidine Drugs in African Trypanosomes

Daniel J. Bridges, Matthew K. Gould, Barbara Nerima, Pascal Mäser, Richard J. S. Burchmore and Harry P. de Koning
Molecular Pharmacology April 1, 2007, 71 (4) 1098-1108; DOI: https://doi.org/10.1124/mol.106.031351
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