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Research ArticleArticle

Positive Allosteric Modulation of the α7 Nicotinic Acetylcholine Receptor: Ligand Interactions with Distinct Binding Sites and Evidence for a Prominent Role of the M2-M3 Segment

Daniel Bertrand, Sonia Bertrand, Steven Cassar, Earl Gubbins, Jinhe Li and M. Gopalakrishnan
Molecular Pharmacology November 2008, 74 (5) 1407-1416; DOI: https://doi.org/10.1124/mol.107.042820

Article Information

vol. 74 no. 5 1407-1416
DOI 
https://doi.org/10.1124/mol.107.042820
PubMed 
18678621
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received October 19, 2007
  • Accepted August 1, 2008
  • Published online October 20, 2008.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Daniel Bertrand,
  2. Sonia Bertrand,
  3. Steven Cassar,
  4. Earl Gubbins,
  5. Jinhe Li and
  6. M. Gopalakrishnan
  1. Department of Neuroscience, Centre Médical Universitaire, Geneva, Switzerland (D.B., S.B.); and Neuroscience Research, Global Pharmaceutical Research & Development, Abbott Laboratories, Abbott Park, Illinois (S.C., E.G., J.L., M.G.)
  1. Address correspondence to:
    D. Bertrand, Dept of Neuroscience, CMU, 1, rue Michel Servet, CH-1211 Geneva 4, Switzerland. E-mail: daniel.bertrand{at}medecine.unige.ch
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Research ArticleArticle

Positive Allosteric Modulation of the α7 Nicotinic Acetylcholine Receptor: Ligand Interactions with Distinct Binding Sites and Evidence for a Prominent Role of the M2-M3 Segment

Daniel Bertrand, Sonia Bertrand, Steven Cassar, Earl Gubbins, Jinhe Li and M. Gopalakrishnan
Molecular Pharmacology November 1, 2008, 74 (5) 1407-1416; DOI: https://doi.org/10.1124/mol.107.042820
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