Index by author
October 01, 2010; Volume 78,Issue 4
A
Abankwa, Daniel
- You have accessAn N-Terminal Polybasic Motif of Gαq Is Required for Signaling and Influences Membrane Nanodomain DistributionMarykate Crouthamel, Daniel Abankwa, Li Zhang, Cherisse DiLizio, David R. Manning, John F. Hancock and Philip B. WedegaertnerMolecular Pharmacology October 2010, 78 (4) 767-777; DOI: https://doi.org/10.1124/mol.110.066340
Abood, Mary E.
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Adler, Martin W.
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Adorini, Luciano
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Aguilar, Marie-Isabel
- You have accessLigand-Supported Purification of the Urotensin-II ReceptorAnn T. Du, Döne Onan, Diem T. Dinh, Michael J. Lew, James Ziogas, Marie-Isabel Aguilar, Leonard K. Pattenden and Walter G. ThomasMolecular Pharmacology October 2010, 78 (4) 639-647; DOI: https://doi.org/10.1124/mol.110.065151
Al-Sabah, Suleiman
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Albiston, Anthony L.
- You have accessPhenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated AminopeptidaseAnthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker and Siew Yeen ChaiMolecular Pharmacology October 2010, 78 (4) 600-607; DOI: https://doi.org/10.1124/mol.110.065458
Altman, Jessica K.
- You have accessNegative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic ResponsesJessica K. Altman, Heather Glaser, Antonella Sassano, Sonali Joshi, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Martin S. Tallman and Leonidas C. PlataniasMolecular Pharmacology October 2010, 78 (4) 778-784; DOI: https://doi.org/10.1124/mol.110.064642
B
Bai, Yushi
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Bailey, Chris P.
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Baptist, Myma
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Barak, Larry S.
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Bee, Thomas
- You have accessElimination of a Hydroxyl Group in FTY720 Dramatically Improves the Phosphorylation RateEve Jary, Thomas Bee, Scott R. Walker, Sung-Kee Chung, Kyung-Chang Seo, Jonathan C. Morris and Anthony S. DonMolecular Pharmacology October 2010, 78 (4) 685-692; DOI: https://doi.org/10.1124/mol.110.064873
Beedanagari, Sudheer R.
- You have accessRole of Epigenetic Mechanisms in Differential Regulation of the Dioxin-Inducible Human CYP1A1 and CYP1B1 GenesSudheer R. Beedanagari, Robert T. Taylor, Peter Bui, Feng Wang, Derek W. Nickerson and Oliver HankinsonMolecular Pharmacology October 2010, 78 (4) 608-616; DOI: https://doi.org/10.1124/mol.110.064899
Bodendiek, Silke B.
- You have accessPotassium Channel Block by a Tripartite Complex of Two Cationophilic Ligands and a Potassium IonPavel I. Zimin, Bojan Garic, Silke B. Bodendiek, Cédrick Mahieux, Heike Wulff and Boris S. ZhorovMolecular Pharmacology October 2010, 78 (4) 588-599; DOI: https://doi.org/10.1124/mol.110.064014
Brazier, Michel
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
Brown, Edward Meigs
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
Bui, Peter
- You have accessRole of Epigenetic Mechanisms in Differential Regulation of the Dioxin-Inducible Human CYP1A1 and CYP1B1 GenesSudheer R. Beedanagari, Robert T. Taylor, Peter Bui, Feng Wang, Derek W. Nickerson and Oliver HankinsonMolecular Pharmacology October 2010, 78 (4) 608-616; DOI: https://doi.org/10.1124/mol.110.064899
C
Caron, Marc G.
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Caudrillier, Axelle
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
Chai, Siew Yeen
- You have accessPhenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated AminopeptidaseAnthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker and Siew Yeen ChaiMolecular Pharmacology October 2010, 78 (4) 600-607; DOI: https://doi.org/10.1124/mol.110.065458
Chan, Eric Chun Yong
- You have accessMechanism-Based Inactivation of Cytochrome P450 3A4 by LapatinibWoon Chien Teng, Jing Wen Oh, Lee Sun New, Michelle D. Wahlin, Sidney D. Nelson, Han Kiat Ho and Eric Chun Yong ChanMolecular Pharmacology October 2010, 78 (4) 693-703; DOI: https://doi.org/10.1124/mol.110.065839
Chang, Min-Hwang
- You have accessTargeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. MatherlyMolecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
Charlton, Steven J.
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Chen, Wei
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Cherian, Christina
- You have accessTargeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. MatherlyMolecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
Chung, Sung-Kee
- You have accessElimination of a Hydroxyl Group in FTY720 Dramatically Improves the Phosphorylation RateEve Jary, Thomas Bee, Scott R. Walker, Sung-Kee Chung, Kyung-Chang Seo, Jonathan C. Morris and Anthony S. DonMolecular Pharmacology October 2010, 78 (4) 685-692; DOI: https://doi.org/10.1124/mol.110.064873
Chung, Thomas D.Y.
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Ciaccioli, Gianmario
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Cortés, Lorena
- You have accessBlockade by Nanomolar Resveratrol of Quantal Catecholamine Release in Chromaffin CellsJosé Carlos Fernández-Morales, Matilde Yáñez, Francisco Orallo, Lorena Cortés, José Carlos González, Jesús Miguel Hernández-Guijo, Antonio G. García and Antonio M. G. de DiegoMolecular Pharmacology October 2010, 78 (4) 734-744; DOI: https://doi.org/10.1124/mol.110.066423
Cournarie, Fabienne
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
Cowan, Alan
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Crouthamel, Marykate
- You have accessAn N-Terminal Polybasic Motif of Gαq Is Required for Signaling and Influences Membrane Nanodomain DistributionMarykate Crouthamel, Daniel Abankwa, Li Zhang, Cherisse DiLizio, David R. Manning, John F. Hancock and Philip B. WedegaertnerMolecular Pharmacology October 2010, 78 (4) 767-777; DOI: https://doi.org/10.1124/mol.110.066340
D
de Diego, Antonio M. G.
- You have accessBlockade by Nanomolar Resveratrol of Quantal Catecholamine Release in Chromaffin CellsJosé Carlos Fernández-Morales, Matilde Yáñez, Francisco Orallo, Lorena Cortés, José Carlos González, Jesús Miguel Hernández-Guijo, Antonio G. García and Antonio M. G. de DiegoMolecular Pharmacology October 2010, 78 (4) 734-744; DOI: https://doi.org/10.1124/mol.110.066423
De Franco, Francesca
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Desmoulin, Sita Kugel
- You have accessTargeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. MatherlyMolecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
Dewey, William L.
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Díez-Dacal, Beatriz
- You have accessCyclopentenone Prostaglandins with Dienone Structure Promote Cross-Linking of the Chemoresistance-Inducing Enzyme Glutathione Transferase P1-1Francisco J. Sánchez-Gómez, Beatriz Díez-Dacal, María A. Pajares, Oscar Llorca and Dolores Pérez-SalaMolecular Pharmacology October 2010, 78 (4) 723-733; DOI: https://doi.org/10.1124/mol.110.065391
DiLizio, Cherisse
- You have accessAn N-Terminal Polybasic Motif of Gαq Is Required for Signaling and Influences Membrane Nanodomain DistributionMarykate Crouthamel, Daniel Abankwa, Li Zhang, Cherisse DiLizio, David R. Manning, John F. Hancock and Philip B. WedegaertnerMolecular Pharmacology October 2010, 78 (4) 767-777; DOI: https://doi.org/10.1124/mol.110.066340
Dinh, Diem T.
- You have accessLigand-Supported Purification of the Urotensin-II ReceptorAnn T. Du, Döne Onan, Diem T. Dinh, Michael J. Lew, James Ziogas, Marie-Isabel Aguilar, Leonard K. Pattenden and Walter G. ThomasMolecular Pharmacology October 2010, 78 (4) 639-647; DOI: https://doi.org/10.1124/mol.110.065151
Don, Anthony S.
- You have accessElimination of a Hydroxyl Group in FTY720 Dramatically Improves the Phosphorylation RateEve Jary, Thomas Bee, Scott R. Walker, Sung-Kee Chung, Kyung-Chang Seo, Jonathan C. Morris and Anthony S. DonMolecular Pharmacology October 2010, 78 (4) 685-692; DOI: https://doi.org/10.1124/mol.110.064873
Donadio, Loredana
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Du, Ann T.
- You have accessLigand-Supported Purification of the Urotensin-II ReceptorAnn T. Du, Döne Onan, Diem T. Dinh, Michael J. Lew, James Ziogas, Marie-Isabel Aguilar, Leonard K. Pattenden and Walter G. ThomasMolecular Pharmacology October 2010, 78 (4) 639-647; DOI: https://doi.org/10.1124/mol.110.065151
E
Ehlert, Frederick J.
- You have accessMutagenesis of Nucleophilic Residues near the Orthosteric Binding Pocket of M1 and M2 Muscarinic receptors: Effect on the Binding of Nitrogen Mustard Analogs of Acetylcholine and McN-A-343Hinako Suga, Gregory W. Sawyer and Frederick J. EhlertMolecular Pharmacology October 2010, 78 (4) 745-755; DOI: https://doi.org/10.1124/mol.110.065367
English, Dallas R.
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
F
Faure, Helene
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
Ferguson, Stephen S.
- You have accessSynergistically Enhanced CYP2B6 Inducibility between a Polymorphic Mutation in CYP2B6 Promoter and Pregnane X Receptor ActivationHaishan Li, Stephen S. Ferguson and Hongbing WangMolecular Pharmacology October 2010, 78 (4) 704-713; DOI: https://doi.org/10.1124/mol.110.065185
Fernández-Morales, José Carlos
- You have accessBlockade by Nanomolar Resveratrol of Quantal Catecholamine Release in Chromaffin CellsJosé Carlos Fernández-Morales, Matilde Yáñez, Francisco Orallo, Lorena Cortés, José Carlos González, Jesús Miguel Hernández-Guijo, Antonio G. García and Antonio M. G. de DiegoMolecular Pharmacology October 2010, 78 (4) 734-744; DOI: https://doi.org/10.1124/mol.110.066423
Fozzard, Harry A.
- You have accessMolecular Model of Anticonvulsant Drug Binding to the Voltage-Gated Sodium Channel Inner PoreGregory M. Lipkind and Harry A. FozzardMolecular Pharmacology October 2010, 78 (4) 631-638; DOI: https://doi.org/10.1124/mol.110.064683
Fukunaga, Rikiro
- You have accessNegative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic ResponsesJessica K. Altman, Heather Glaser, Antonella Sassano, Sonali Joshi, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Martin S. Tallman and Leonidas C. PlataniasMolecular Pharmacology October 2010, 78 (4) 778-784; DOI: https://doi.org/10.1124/mol.110.064642
Fulterer, Andreas
- You have accessTargeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. MatherlyMolecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
Furukawa, Hiro
- You have accessControl of Assembly and Function of Glutamate Receptors by the Amino-Terminal DomainKasper B. Hansen, Hiro Furukawa and Stephen F. TraynelisMolecular Pharmacology October 2010, 78 (4) 535-549; DOI: https://doi.org/10.1124/mol.110.067157
G
Gangjee, Aleem
- You have accessTargeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. MatherlyMolecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
García, Antonio G.
- You have accessBlockade by Nanomolar Resveratrol of Quantal Catecholamine Release in Chromaffin CellsJosé Carlos Fernández-Morales, Matilde Yáñez, Francisco Orallo, Lorena Cortés, José Carlos González, Jesús Miguel Hernández-Guijo, Antonio G. García and Antonio M. G. de DiegoMolecular Pharmacology October 2010, 78 (4) 734-744; DOI: https://doi.org/10.1124/mol.110.066423
Gardner-Stephen, Dione
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
Garic, Bojan
- You have accessPotassium Channel Block by a Tripartite Complex of Two Cationophilic Ligands and a Potassium IonPavel I. Zimin, Bojan Garic, Silke B. Bodendiek, Cédrick Mahieux, Heike Wulff and Boris S. ZhorovMolecular Pharmacology October 2010, 78 (4) 588-599; DOI: https://doi.org/10.1124/mol.110.064014
Geller, Ellen B.
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Giles, Graham G.
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
Gkountelias, Kostas
- You have accessExploring the Binding Site Crevice of a Family B G Protein-Coupled Receptor, the Type 1 Corticotropin Releasing Factor ReceptorKostas Gkountelias, Maria Papadokostaki, Jonathan A. Javitch and George LiapakisMolecular Pharmacology October 2010, 78 (4) 785-793; DOI: https://doi.org/10.1124/mol.110.065474
Glaser, Heather
- You have accessNegative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic ResponsesJessica K. Altman, Heather Glaser, Antonella Sassano, Sonali Joshi, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Martin S. Tallman and Leonidas C. PlataniasMolecular Pharmacology October 2010, 78 (4) 778-784; DOI: https://doi.org/10.1124/mol.110.064642
Godin, Corinne
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
González, José Carlos
- You have accessBlockade by Nanomolar Resveratrol of Quantal Catecholamine Release in Chromaffin CellsJosé Carlos Fernández-Morales, Matilde Yáñez, Francisco Orallo, Lorena Cortés, José Carlos González, Jesús Miguel Hernández-Guijo, Antonio G. García and Antonio M. G. de DiegoMolecular Pharmacology October 2010, 78 (4) 734-744; DOI: https://doi.org/10.1124/mol.110.066423
Gorojankina, Tatiana
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
Gregory, Philip A.
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
H
Hancock, John F.
- You have accessAn N-Terminal Polybasic Motif of Gαq Is Required for Signaling and Influences Membrane Nanodomain DistributionMarykate Crouthamel, Daniel Abankwa, Li Zhang, Cherisse DiLizio, David R. Manning, John F. Hancock and Philip B. WedegaertnerMolecular Pharmacology October 2010, 78 (4) 767-777; DOI: https://doi.org/10.1124/mol.110.066340
Hankinson, Oliver
- You have accessRole of Epigenetic Mechanisms in Differential Regulation of the Dioxin-Inducible Human CYP1A1 and CYP1B1 GenesSudheer R. Beedanagari, Robert T. Taylor, Peter Bui, Feng Wang, Derek W. Nickerson and Oliver HankinsonMolecular Pharmacology October 2010, 78 (4) 608-616; DOI: https://doi.org/10.1124/mol.110.064899
Hansen, Kasper B.
- You have accessControl of Assembly and Function of Glutamate Receptors by the Amino-Terminal DomainKasper B. Hansen, Hiro Furukawa and Stephen F. TraynelisMolecular Pharmacology October 2010, 78 (4) 535-549; DOI: https://doi.org/10.1124/mol.110.067157
Henderson, Graeme
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Hernández-Guijo, Jesús Miguel
- You have accessBlockade by Nanomolar Resveratrol of Quantal Catecholamine Release in Chromaffin CellsJosé Carlos Fernández-Morales, Matilde Yáñez, Francisco Orallo, Lorena Cortés, José Carlos González, Jesús Miguel Hernández-Guijo, Antonio G. García and Antonio M. G. de DiegoMolecular Pharmacology October 2010, 78 (4) 734-744; DOI: https://doi.org/10.1124/mol.110.066423
Heynen-Genel, Susanne
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Ho, Han Kiat
- You have accessMechanism-Based Inactivation of Cytochrome P450 3A4 by LapatinibWoon Chien Teng, Jing Wen Oh, Lee Sun New, Michelle D. Wahlin, Sidney D. Nelson, Han Kiat Ho and Eric Chun Yong ChanMolecular Pharmacology October 2010, 78 (4) 693-703; DOI: https://doi.org/10.1124/mol.110.065839
Holien, Jessica K.
- You have accessPhenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated AminopeptidaseAnthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker and Siew Yeen ChaiMolecular Pharmacology October 2010, 78 (4) 600-607; DOI: https://doi.org/10.1124/mol.110.065458
Hopper, John L.
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
Hou, Zhanjun
- You have accessTargeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. MatherlyMolecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
Hu, Dong Gui
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
Hurtel-Lemaire, Anne-Sophie
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
J
Jacobson, Marlene A.
- You have accessThe M1 Muscarinic Receptor Allosteric Agonists AC-42 and 1-[1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one Bind to a Unique Site Distinct from the Acetylcholine Orthosteric SiteMarlene A. Jacobson, Constantine Kreatsoulas, Danette M. Pascarella, Julie A. O'Brien and Cyrille SurMolecular Pharmacology October 2010, 78 (4) 648-657; DOI: https://doi.org/10.1124/mol.110.065771
Jary, Eve
- You have accessElimination of a Hydroxyl Group in FTY720 Dramatically Improves the Phosphorylation RateEve Jary, Thomas Bee, Scott R. Walker, Sung-Kee Chung, Kyung-Chang Seo, Jonathan C. Morris and Anthony S. DonMolecular Pharmacology October 2010, 78 (4) 685-692; DOI: https://doi.org/10.1124/mol.110.064873
Javitch, Jonathan A.
- You have accessExploring the Binding Site Crevice of a Family B G Protein-Coupled Receptor, the Type 1 Corticotropin Releasing Factor ReceptorKostas Gkountelias, Maria Papadokostaki, Jonathan A. Javitch and George LiapakisMolecular Pharmacology October 2010, 78 (4) 785-793; DOI: https://doi.org/10.1124/mol.110.065474
Jiang, Tao
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Joshi, Sonali
- You have accessNegative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic ResponsesJessica K. Altman, Heather Glaser, Antonella Sassano, Sonali Joshi, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Martin S. Tallman and Leonidas C. PlataniasMolecular Pharmacology October 2010, 78 (4) 778-784; DOI: https://doi.org/10.1124/mol.110.064642
K
Kalinowski, Danuta S.
- You have accessMembrane Transport and Intracellular Sequestration of Novel Thiosemicarbazone Chelators for the Treatment of CancerAngelica M. Merlot, Namfon Pantarat, David B. Lovejoy, Danuta S. Kalinowski and Des R. RichardsonMolecular Pharmacology October 2010, 78 (4) 675-684; DOI: https://doi.org/10.1124/mol.110.066126
Kamel, Said
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
Kapur, Ankur
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Kelly, Eamonn
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Khadem, Shaheen
- You have accessA Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesYonggong Zhai, Tara Wada, Bin Zhang, Shaheen Khadem, Songrong Ren, Ramalinga Kuruba, Song Li and Wen XieMolecular Pharmacology October 2010, 78 (4) 666-674; DOI: https://doi.org/10.1124/mol.110.064618
Krasel, Cornelius
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Kreatsoulas, Constantine
- You have accessThe M1 Muscarinic Receptor Allosteric Agonists AC-42 and 1-[1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one Bind to a Unique Site Distinct from the Acetylcholine Orthosteric SiteMarlene A. Jacobson, Constantine Kreatsoulas, Danette M. Pascarella, Julie A. O'Brien and Cyrille SurMolecular Pharmacology October 2010, 78 (4) 648-657; DOI: https://doi.org/10.1124/mol.110.065771
Kuruba, Ramalinga
- You have accessA Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesYonggong Zhai, Tara Wada, Bin Zhang, Shaheen Khadem, Songrong Ren, Ramalinga Kuruba, Song Li and Wen XieMolecular Pharmacology October 2010, 78 (4) 666-674; DOI: https://doi.org/10.1124/mol.110.064618
L
Levi, Moshe
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Lew, Michael J.
- You have accessLigand-Supported Purification of the Urotensin-II ReceptorAnn T. Du, Döne Onan, Diem T. Dinh, Michael J. Lew, James Ziogas, Marie-Isabel Aguilar, Leonard K. Pattenden and Walter G. ThomasMolecular Pharmacology October 2010, 78 (4) 639-647; DOI: https://doi.org/10.1124/mol.110.065151
Lew, Rebecca A.
- You have accessPhenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated AminopeptidaseAnthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker and Siew Yeen ChaiMolecular Pharmacology October 2010, 78 (4) 600-607; DOI: https://doi.org/10.1124/mol.110.065458
Li, Haishan
- You have accessSynergistically Enhanced CYP2B6 Inducibility between a Polymorphic Mutation in CYP2B6 Promoter and Pregnane X Receptor ActivationHaishan Li, Stephen S. Ferguson and Hongbing WangMolecular Pharmacology October 2010, 78 (4) 704-713; DOI: https://doi.org/10.1124/mol.110.065185
Li, Song
- You have accessA Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesYonggong Zhai, Tara Wada, Bin Zhang, Shaheen Khadem, Songrong Ren, Ramalinga Kuruba, Song Li and Wen XieMolecular Pharmacology October 2010, 78 (4) 666-674; DOI: https://doi.org/10.1124/mol.110.064618
Liapakis, George
- You have accessExploring the Binding Site Crevice of a Family B G Protein-Coupled Receptor, the Type 1 Corticotropin Releasing Factor ReceptorKostas Gkountelias, Maria Papadokostaki, Jonathan A. Javitch and George LiapakisMolecular Pharmacology October 2010, 78 (4) 785-793; DOI: https://doi.org/10.1124/mol.110.065474
Lipkind, Gregory M.
- You have accessMolecular Model of Anticonvulsant Drug Binding to the Voltage-Gated Sodium Channel Inner PoreGregory M. Lipkind and Harry A. FozzardMolecular Pharmacology October 2010, 78 (4) 631-638; DOI: https://doi.org/10.1124/mol.110.064683
Llorca, Oscar
- You have accessCyclopentenone Prostaglandins with Dienone Structure Promote Cross-Linking of the Chemoresistance-Inducing Enzyme Glutathione Transferase P1-1Francisco J. Sánchez-Gómez, Beatriz Díez-Dacal, María A. Pajares, Oscar Llorca and Dolores Pérez-SalaMolecular Pharmacology October 2010, 78 (4) 723-733; DOI: https://doi.org/10.1124/mol.110.065391
Llorente, Javier
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Lovejoy, David B.
- You have accessMembrane Transport and Intracellular Sequestration of Novel Thiosemicarbazone Chelators for the Treatment of CancerAngelica M. Merlot, Namfon Pantarat, David B. Lovejoy, Danuta S. Kalinowski and Des R. RichardsonMolecular Pharmacology October 2010, 78 (4) 675-684; DOI: https://doi.org/10.1124/mol.110.066126
M
Mackenzie, Peter I.
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
Mahieux, Cédrick
- You have accessPotassium Channel Block by a Tripartite Complex of Two Cationophilic Ligands and a Potassium IonPavel I. Zimin, Bojan Garic, Silke B. Bodendiek, Cédrick Mahieux, Heike Wulff and Boris S. ZhorovMolecular Pharmacology October 2010, 78 (4) 588-599; DOI: https://doi.org/10.1124/mol.110.064014
Manetti, Fabrizio
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
Mann, Andre
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
Manning, David R.
- You have accessAn N-Terminal Polybasic Motif of Gαq Is Required for Signaling and Influences Membrane Nanodomain DistributionMarykate Crouthamel, Daniel Abankwa, Li Zhang, Cherisse DiLizio, David R. Manning, John F. Hancock and Philip B. WedegaertnerMolecular Pharmacology October 2010, 78 (4) 767-777; DOI: https://doi.org/10.1124/mol.110.066340
Matherly, Larry H.
- You have accessTargeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. MatherlyMolecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
McPherson, Jamie
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Mentaverri, Romuald
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
Merlot, Angelica M.
- You have accessMembrane Transport and Intracellular Sequestration of Novel Thiosemicarbazone Chelators for the Treatment of CancerAngelica M. Merlot, Namfon Pantarat, David B. Lovejoy, Danuta S. Kalinowski and Des R. RichardsonMolecular Pharmacology October 2010, 78 (4) 675-684; DOI: https://doi.org/10.1124/mol.110.066126
Morris, Jonathan C.
- You have accessElimination of a Hydroxyl Group in FTY720 Dramatically Improves the Phosphorylation RateEve Jary, Thomas Bee, Scott R. Walker, Sung-Kee Chung, Kyung-Chang Seo, Jonathan C. Morris and Anthony S. DonMolecular Pharmacology October 2010, 78 (4) 685-692; DOI: https://doi.org/10.1124/mol.110.064873
Morton, Craig J.
- You have accessPhenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated AminopeptidaseAnthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker and Siew Yeen ChaiMolecular Pharmacology October 2010, 78 (4) 600-607; DOI: https://doi.org/10.1124/mol.110.065458
N
Nelson, Sidney D.
- You have accessMechanism-Based Inactivation of Cytochrome P450 3A4 by LapatinibWoon Chien Teng, Jing Wen Oh, Lee Sun New, Michelle D. Wahlin, Sidney D. Nelson, Han Kiat Ho and Eric Chun Yong ChanMolecular Pharmacology October 2010, 78 (4) 693-703; DOI: https://doi.org/10.1124/mol.110.065839
Neubig, Richard R.
- You have accessThinking Outside of the “RGS Box”: New Approaches to Therapeutic Targeting of Regulators of G Protein SignalingBenita Sjögren and Richard R. NeubigMolecular Pharmacology October 2010, 78 (4) 550-557; DOI: https://doi.org/10.1124/mol.110.065219
- You have accessMind Your Salts: When the Inactive Constituent Isn'tRichard R. NeubigMolecular Pharmacology October 2010, 78 (4) 558-559; DOI: https://doi.org/10.1124/mol.110.067645
New, Lee Sun
- You have accessMechanism-Based Inactivation of Cytochrome P450 3A4 by LapatinibWoon Chien Teng, Jing Wen Oh, Lee Sun New, Michelle D. Wahlin, Sidney D. Nelson, Han Kiat Ho and Eric Chun Yong ChanMolecular Pharmacology October 2010, 78 (4) 693-703; DOI: https://doi.org/10.1124/mol.110.065839
Ng, Leelee
- You have accessPhenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated AminopeptidaseAnthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker and Siew Yeen ChaiMolecular Pharmacology October 2010, 78 (4) 600-607; DOI: https://doi.org/10.1124/mol.110.065458
Nickerson, Derek W.
- You have accessRole of Epigenetic Mechanisms in Differential Regulation of the Dioxin-Inducible Human CYP1A1 and CYP1B1 GenesSudheer R. Beedanagari, Robert T. Taylor, Peter Bui, Feng Wang, Derek W. Nickerson and Oliver HankinsonMolecular Pharmacology October 2010, 78 (4) 608-616; DOI: https://doi.org/10.1124/mol.110.064899
O
O'Brien, Julie A.
- You have accessThe M1 Muscarinic Receptor Allosteric Agonists AC-42 and 1-[1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one Bind to a Unique Site Distinct from the Acetylcholine Orthosteric SiteMarlene A. Jacobson, Constantine Kreatsoulas, Danette M. Pascarella, Julie A. O'Brien and Cyrille SurMolecular Pharmacology October 2010, 78 (4) 648-657; DOI: https://doi.org/10.1124/mol.110.065771
Oh, Jing Wen
- You have accessMechanism-Based Inactivation of Cytochrome P450 3A4 by LapatinibWoon Chien Teng, Jing Wen Oh, Lee Sun New, Michelle D. Wahlin, Sidney D. Nelson, Han Kiat Ho and Eric Chun Yong ChanMolecular Pharmacology October 2010, 78 (4) 693-703; DOI: https://doi.org/10.1124/mol.110.065839
Onan, Döne
- You have accessLigand-Supported Purification of the Urotensin-II ReceptorAnn T. Du, Döne Onan, Diem T. Dinh, Michael J. Lew, James Ziogas, Marie-Isabel Aguilar, Leonard K. Pattenden and Walter G. ThomasMolecular Pharmacology October 2010, 78 (4) 639-647; DOI: https://doi.org/10.1124/mol.110.065151
Orallo, Francisco
- You have accessBlockade by Nanomolar Resveratrol of Quantal Catecholamine Release in Chromaffin CellsJosé Carlos Fernández-Morales, Matilde Yáñez, Francisco Orallo, Lorena Cortés, José Carlos González, Jesús Miguel Hernández-Guijo, Antonio G. García and Antonio M. G. de DiegoMolecular Pharmacology October 2010, 78 (4) 734-744; DOI: https://doi.org/10.1124/mol.110.066423
Orlandi, Stefano
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
P
Pajares, María A.
- You have accessCyclopentenone Prostaglandins with Dienone Structure Promote Cross-Linking of the Chemoresistance-Inducing Enzyme Glutathione Transferase P1-1Francisco J. Sánchez-Gómez, Beatriz Díez-Dacal, María A. Pajares, Oscar Llorca and Dolores Pérez-SalaMolecular Pharmacology October 2010, 78 (4) 723-733; DOI: https://doi.org/10.1124/mol.110.065391
Pantarat, Namfon
- You have accessMembrane Transport and Intracellular Sequestration of Novel Thiosemicarbazone Chelators for the Treatment of CancerAngelica M. Merlot, Namfon Pantarat, David B. Lovejoy, Danuta S. Kalinowski and Des R. RichardsonMolecular Pharmacology October 2010, 78 (4) 675-684; DOI: https://doi.org/10.1124/mol.110.066126
Papadokostaki, Maria
- You have accessExploring the Binding Site Crevice of a Family B G Protein-Coupled Receptor, the Type 1 Corticotropin Releasing Factor ReceptorKostas Gkountelias, Maria Papadokostaki, Jonathan A. Javitch and George LiapakisMolecular Pharmacology October 2010, 78 (4) 785-793; DOI: https://doi.org/10.1124/mol.110.065474
Parker, Michael W.
- You have accessPhenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated AminopeptidaseAnthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker and Siew Yeen ChaiMolecular Pharmacology October 2010, 78 (4) 600-607; DOI: https://doi.org/10.1124/mol.110.065458
Pascarella, Danette M.
- You have accessThe M1 Muscarinic Receptor Allosteric Agonists AC-42 and 1-[1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one Bind to a Unique Site Distinct from the Acetylcholine Orthosteric SiteMarlene A. Jacobson, Constantine Kreatsoulas, Danette M. Pascarella, Julie A. O'Brien and Cyrille SurMolecular Pharmacology October 2010, 78 (4) 648-657; DOI: https://doi.org/10.1124/mol.110.065771
Passeri, Daniela
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Pattenden, Leonard K.
- You have accessLigand-Supported Purification of the Urotensin-II ReceptorAnn T. Du, Döne Onan, Diem T. Dinh, Michael J. Lew, James Ziogas, Marie-Isabel Aguilar, Leonard K. Pattenden and Walter G. ThomasMolecular Pharmacology October 2010, 78 (4) 639-647; DOI: https://doi.org/10.1124/mol.110.065151
Pérez-Sala, Dolores
- You have accessCyclopentenone Prostaglandins with Dienone Structure Promote Cross-Linking of the Chemoresistance-Inducing Enzyme Glutathione Transferase P1-1Francisco J. Sánchez-Gómez, Beatriz Díez-Dacal, María A. Pajares, Oscar Llorca and Dolores Pérez-SalaMolecular Pharmacology October 2010, 78 (4) 723-733; DOI: https://doi.org/10.1124/mol.110.065391
Petit, Jean-Pierre
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
Petit, Laurent
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
Pham, Vi
- You have accessPhenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated AminopeptidaseAnthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker and Siew Yeen ChaiMolecular Pharmacology October 2010, 78 (4) 600-607; DOI: https://doi.org/10.1124/mol.110.065458
Platanias, Leonidas C.
- You have accessNegative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic ResponsesJessica K. Altman, Heather Glaser, Antonella Sassano, Sonali Joshi, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Martin S. Tallman and Leonidas C. PlataniasMolecular Pharmacology October 2010, 78 (4) 778-784; DOI: https://doi.org/10.1124/mol.110.064642
Pruzanski, Mark
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
R
Reggio, Patricia H.
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Ren, Songrong
- You have accessA Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesYonggong Zhai, Tara Wada, Bin Zhang, Shaheen Khadem, Songrong Ren, Ramalinga Kuruba, Song Li and Wen XieMolecular Pharmacology October 2010, 78 (4) 666-674; DOI: https://doi.org/10.1124/mol.110.064618
Richardson, Des R.
- You have accessMembrane Transport and Intracellular Sequestration of Novel Thiosemicarbazone Chelators for the Treatment of CancerAngelica M. Merlot, Namfon Pantarat, David B. Lovejoy, Danuta S. Kalinowski and Des R. RichardsonMolecular Pharmacology October 2010, 78 (4) 675-684; DOI: https://doi.org/10.1124/mol.110.066126
Rivero, Guadalupe
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Rizzo, Giorgia
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Rizzo, Giovanni
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Romero, Michael F.
- You have accessTargeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. MatherlyMolecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
Rosethorne, Elizabeth M.
- You have accessμ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate InternalizationJamie McPherson, Guadalupe Rivero, Myma Baptist, Javier Llorente, Suleiman Al-Sabah, Cornelius Krasel, William L. Dewey, Chris P. Bailey, Elizabeth M. Rosethorne, Steven J. Charlton, Graeme Henderson and Eamonn KellyMolecular Pharmacology October 2010, 78 (4) 756-766; DOI: https://doi.org/10.1124/mol.110.066613
Roudaut, Hermine
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
Ruat, Martial
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
S
Sadeghpour, Bahman
- You have accessFunctional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistGiovanni Rizzo, Daniela Passeri, Francesca De Franco, Gianmario Ciaccioli, Loredana Donadio, Giorgia Rizzo, Stefano Orlandi, Bahman Sadeghpour, Xiaoxin X. Wang, Tao Jiang, Moshe Levi, Mark Pruzanski and Luciano AdoriniMolecular Pharmacology October 2010, 78 (4) 617-630; DOI: https://doi.org/10.1124/mol.110.064501
Sánchez-Gómez, Francisco J.
- You have accessCyclopentenone Prostaglandins with Dienone Structure Promote Cross-Linking of the Chemoresistance-Inducing Enzyme Glutathione Transferase P1-1Francisco J. Sánchez-Gómez, Beatriz Díez-Dacal, María A. Pajares, Oscar Llorca and Dolores Pérez-SalaMolecular Pharmacology October 2010, 78 (4) 723-733; DOI: https://doi.org/10.1124/mol.110.065391
Sassano, Antonella
- You have accessNegative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic ResponsesJessica K. Altman, Heather Glaser, Antonella Sassano, Sonali Joshi, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Martin S. Tallman and Leonidas C. PlataniasMolecular Pharmacology October 2010, 78 (4) 778-784; DOI: https://doi.org/10.1124/mol.110.064642
Sauer, Michelle
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Sawyer, Gregory W.
- You have accessMutagenesis of Nucleophilic Residues near the Orthosteric Binding Pocket of M1 and M2 Muscarinic receptors: Effect on the Binding of Nitrogen Mustard Analogs of Acetylcholine and McN-A-343Hinako Suga, Gregory W. Sawyer and Frederick J. EhlertMolecular Pharmacology October 2010, 78 (4) 745-755; DOI: https://doi.org/10.1124/mol.110.065367
Schoenfelder, Angele
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
Seltzman, Herbert H.
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Seo, Kyung-Chang
- You have accessElimination of a Hydroxyl Group in FTY720 Dramatically Improves the Phosphorylation RateEve Jary, Thomas Bee, Scott R. Walker, Sung-Kee Chung, Kyung-Chang Seo, Jonathan C. Morris and Anthony S. DonMolecular Pharmacology October 2010, 78 (4) 685-692; DOI: https://doi.org/10.1124/mol.110.064873
Severi, Gianluca
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
Sharir, Haleli
- You have accessTargeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and β-Arrestin2 with Antinociceptive ActivityPingwei Zhao, Haleli Sharir, Ankur Kapur, Alan Cowan, Ellen B. Geller, Martin W. Adler, Herbert H. Seltzman, Patricia H. Reggio, Susanne Heynen-Genel, Michelle Sauer, Thomas D.Y. Chung, Yushi Bai, Wei Chen, Marc G. Caron, Larry S. Barak and Mary E. AboodMolecular Pharmacology October 2010, 78 (4) 560-568; DOI: https://doi.org/10.1124/mol.110.066746
Sjögren, Benita
- You have accessThinking Outside of the “RGS Box”: New Approaches to Therapeutic Targeting of Regulators of G Protein SignalingBenita Sjögren and Richard R. NeubigMolecular Pharmacology October 2010, 78 (4) 550-557; DOI: https://doi.org/10.1124/mol.110.065219
Solinas, Antonio
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
Stout, Mark
- You have accessTargeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid TumorsSita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. MatherlyMolecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
Suga, Hinako
- You have accessMutagenesis of Nucleophilic Residues near the Orthosteric Binding Pocket of M1 and M2 Muscarinic receptors: Effect on the Binding of Nitrogen Mustard Analogs of Acetylcholine and McN-A-343Hinako Suga, Gregory W. Sawyer and Frederick J. EhlertMolecular Pharmacology October 2010, 78 (4) 745-755; DOI: https://doi.org/10.1124/mol.110.065367
Sur, Cyrille
- You have accessThe M1 Muscarinic Receptor Allosteric Agonists AC-42 and 1-[1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one Bind to a Unique Site Distinct from the Acetylcholine Orthosteric SiteMarlene A. Jacobson, Constantine Kreatsoulas, Danette M. Pascarella, Julie A. O'Brien and Cyrille SurMolecular Pharmacology October 2010, 78 (4) 648-657; DOI: https://doi.org/10.1124/mol.110.065771
T
Taddei, Maurizio
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
Tallman, Martin S.
- You have accessNegative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic ResponsesJessica K. Altman, Heather Glaser, Antonella Sassano, Sonali Joshi, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Martin S. Tallman and Leonidas C. PlataniasMolecular Pharmacology October 2010, 78 (4) 778-784; DOI: https://doi.org/10.1124/mol.110.064642
Taylor, Robert T.
- You have accessRole of Epigenetic Mechanisms in Differential Regulation of the Dioxin-Inducible Human CYP1A1 and CYP1B1 GenesSudheer R. Beedanagari, Robert T. Taylor, Peter Bui, Feng Wang, Derek W. Nickerson and Oliver HankinsonMolecular Pharmacology October 2010, 78 (4) 608-616; DOI: https://doi.org/10.1124/mol.110.064899
Teng, Woon Chien
- You have accessMechanism-Based Inactivation of Cytochrome P450 3A4 by LapatinibWoon Chien Teng, Jing Wen Oh, Lee Sun New, Michelle D. Wahlin, Sidney D. Nelson, Han Kiat Ho and Eric Chun Yong ChanMolecular Pharmacology October 2010, 78 (4) 693-703; DOI: https://doi.org/10.1124/mol.110.065839
Terwilliger, Ernest
- You have accessStrontium Ranelate Decreases Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastic Differentiation In Vitro: Involvement of the Calcium-Sensing ReceptorAxelle Caudrillier, Anne-Sophie Hurtel-Lemaire, Alice Wattel, Fabienne Cournarie, Corinne Godin, Laurent Petit, Jean-Pierre Petit, Ernest Terwilliger, Said Kamel, Edward Meigs Brown, Romuald Mentaverri and Michel BrazierMolecular Pharmacology October 2010, 78 (4) 569-576; DOI: https://doi.org/10.1124/mol.109.063347
Thomas, Walter G.
- You have accessLigand-Supported Purification of the Urotensin-II ReceptorAnn T. Du, Döne Onan, Diem T. Dinh, Michael J. Lew, James Ziogas, Marie-Isabel Aguilar, Leonard K. Pattenden and Walter G. ThomasMolecular Pharmacology October 2010, 78 (4) 639-647; DOI: https://doi.org/10.1124/mol.110.065151
Thompson, Philip E.
- You have accessPhenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated AminopeptidaseAnthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker and Siew Yeen ChaiMolecular Pharmacology October 2010, 78 (4) 600-607; DOI: https://doi.org/10.1124/mol.110.065458
Tilley, Wayne D.
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
Traiffort, Elisabeth
- You have accessVirtual Screening-Based Discovery and Mechanistic Characterization of the Acylthiourea MRT-10 Family as Smoothened AntagonistsFabrizio Manetti, Helene Faure, Hermine Roudaut, Tatiana Gorojankina, Elisabeth Traiffort, Angele Schoenfelder, Andre Mann, Antonio Solinas, Maurizio Taddei and Martial RuatMolecular Pharmacology October 2010, 78 (4) 658-665; DOI: https://doi.org/10.1124/mol.110.065102
Traynelis, Stephen F.
- You have accessControl of Assembly and Function of Glutamate Receptors by the Amino-Terminal DomainKasper B. Hansen, Hiro Furukawa and Stephen F. TraynelisMolecular Pharmacology October 2010, 78 (4) 535-549; DOI: https://doi.org/10.1124/mol.110.067157
Treloar, Joanna
- You have accessA Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and Is Associated with Altered Levels of Circulating Androstane-3α,17β-diol GlucuronideDong Gui Hu, Dione Gardner-Stephen, Gianluca Severi, Philip A. Gregory, Joanna Treloar, Graham G. Giles, Dallas R. English, John L. Hopper, Wayne D. Tilley and Peter I. MackenzieMolecular Pharmacology October 2010, 78 (4) 714-722; DOI: https://doi.org/10.1124/mol.110.065953
U
Ueda, Takeshi
- You have accessNegative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic ResponsesJessica K. Altman, Heather Glaser, Antonella Sassano, Sonali Joshi, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Martin S. Tallman and Leonidas C. PlataniasMolecular Pharmacology October 2010, 78 (4) 778-784; DOI: https://doi.org/10.1124/mol.110.064642
W
Wada, Tara
- You have accessA Functional Cross-Talk between Liver X Receptor-α and Constitutive Androstane Receptor Links Lipogenesis and Xenobiotic ResponsesYonggong Zhai, Tara Wada, Bin Zhang, Shaheen Khadem, Songrong Ren, Ramalinga Kuruba, Song Li and Wen XieMolecular Pharmacology October 2010, 78 (4) 666-674; DOI: https://doi.org/10.1124/mol.110.064618
Wahlin, Michelle D.
- You have accessMechanism-Based Inactivation of Cytochrome P450 3A4 by LapatinibWoon Chien Teng, Jing Wen Oh, Lee Sun New, Michelle D. Wahlin, Sidney D. Nelson, Han Kiat Ho and Eric Chun Yong ChanMolecular Pharmacology October 2010, 78 (4) 693-703; DOI: https://doi.org/10.1124/mol.110.065839
Walker, Scott R.
- You have accessElimination of a Hydroxyl Group in FTY720 Dramatically Improves the Phosphorylation RateEve Jary, Thomas Bee, Scott R. Walker, Sung-Kee Chung, Kyung-Chang Seo, Jonathan C. Morris and Anthony S. DonMolecular Pharmacology October 2010, 78 (4) 685-692; DOI: https://doi.org/10.1124/mol.110.064873
Wang, Feng
- You have accessRole of Epigenetic Mechanisms in Differential Regulation of the Dioxin-Inducible Human CYP1A1 and CYP1B1 GenesSudheer R. Beedanagari, Robert T. Taylor, Peter Bui, Feng Wang, Derek W. Nickerson and Oliver HankinsonMolecular Pharmacology October 2010, 78 (4) 608-616; DOI: https://doi.org/10.1124/mol.110.064899
Wang, Hongbing
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Wu, Jianmei
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Zhai, Yonggong
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Zhang, Bin
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