Abstract
The conformation of highly purified acetylcholinesterase was measured with a spectropolarimeter. It was demonstrated that heat, strong base, a substrate, and anticholinesterase agents induce alterations in the conformation of this enzyme.
ACKNOWLEDGMENT This study was supported in part by National Institutes of Health grants GM09069-05, NB 05184, and PH 446454; and National Science Foundation grant GB 5362.
- Copyright ©, 1968, by Academic Press Inc.
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