Research ArticleArticle
Enhanced Degradation of Dihydrofolate Reductase through Inhibition of NAD Kinase by Nicotinamide Analogs
Yi-Ching Hsieh, Philip Tedeschi, Rialnat AdeBisi Lawal, Debabrata Banerjee, Kathleen Scotto, John E. Kerrigan, Kuo-Chieh Lee, Nadine Johnson-Farley, Joseph R. Bertino and Emine Ercikan Abali
Molecular Pharmacology February 2013, 83 (2) 339-353; DOI: https://doi.org/10.1124/mol.112.080218
Yi-Ching Hsieh
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
Philip Tedeschi
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
Rialnat AdeBisi Lawal
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
Debabrata Banerjee
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
Kathleen Scotto
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
John E. Kerrigan
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
Kuo-Chieh Lee
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
Nadine Johnson-Farley
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
Joseph R. Bertino
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
Emine Ercikan Abali
Departments of Pharmacology and Medicine, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey (Y.C.H., P.T., R.A.L., D.B., K.S., J.E.K., K.C.L., N.J.F., J.R.B.); and Department of Biochemistry, Pharmacology and Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway (E.E.A.), New Jersey
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Degradation of DHFR by Thionicotinamide Analogs
Yi-Ching Hsieh, Philip Tedeschi, Rialnat AdeBisi Lawal, Debabrata Banerjee, Kathleen Scotto, John E. Kerrigan, Kuo-Chieh Lee, Nadine Johnson-Farley, Joseph R. Bertino and Emine Ercikan Abali
Molecular Pharmacology February 1, 2013, 83 (2) 339-353; DOI: https://doi.org/10.1124/mol.112.080218
Research ArticleArticle
Degradation of DHFR by Thionicotinamide Analogs
Yi-Ching Hsieh, Philip Tedeschi, Rialnat AdeBisi Lawal, Debabrata Banerjee, Kathleen Scotto, John E. Kerrigan, Kuo-Chieh Lee, Nadine Johnson-Farley, Joseph R. Bertino and Emine Ercikan Abali
Molecular Pharmacology February 1, 2013, 83 (2) 339-353; DOI: https://doi.org/10.1124/mol.112.080218
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