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Observed Drug-Receptor Association Rates Are Governed by Membrane Affinity: The Importance of Establishing “Micro-Pharmacokinetic/Pharmacodynamic Relationships” at the β2-Adrenoceptor

David A. Sykes, Cheryl Parry, John Reilly, Penny Wright, Robin A. Fairhurst and Steven J. Charlton
Molecular Pharmacology April 2014, 85 (4) 608-617; DOI: https://doi.org/10.1124/mol.113.090209
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Research ArticleArticle

Establishing “Micro PK/PD” at the β2-Adrenoceptor

David A. Sykes, Cheryl Parry, John Reilly, Penny Wright, Robin A. Fairhurst and Steven J. Charlton
Molecular Pharmacology April 1, 2014, 85 (4) 608-617; DOI: https://doi.org/10.1124/mol.113.090209
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