Table of Contents

Articles

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  Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor

  Manna Huang, Yongxian Shao, Jianying Hou, Wenjun Cui, Beibei Liang, Yingchun Huang, Zhe Li, Yinuo Wu, Xinhai Zhu, Peiqing Liu, Yiqian Wan, Hengming Ke and Hai-Bin Luo

  Molecular Pharmacology November 2015, 88 (5) 836-845; DOI: https://doi.org/10.1124/mol.115.099747
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  Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action

  Shawn T. Alexander, Thomas Hunter, Sarah Walter, Jin Dong, Derek Maclean, Amos Baruch, Raju Subramanian and James E. Tomlinson

  Molecular Pharmacology November 2015, 88 (5) 853-865; DOI: https://doi.org/10.1124/mol.115.098392
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  Mechanism of Modification, by Lidocaine, of Fast and Slow Recovery from Inactivation of Voltage-Gated Na⁺ Channels

  Vaibhavkumar S. Gawali, Peter Lukacs, Rene Cervenka, Xaver Koenig, Lena Rubi, Karlheinz Hilber, Walter Sandtner and Hannes Todt

  Molecular Pharmacology November 2015, 88 (5) 866-879; DOI: https://doi.org/10.1124/mol.115.099580
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  α-Conotoxins Identify the α3β4* Subtype as the Predominant Nicotinic Acetylcholine Receptor Expressed in Human Adrenal Chromaffin Cells

  Arik J. Hone, J. Michael McIntosh, Layla Azam, Jon Lindstrom, Linda Lucero, Paul Whiteaker, Juan Passas, Jesús Blázquez and Almudena Albillos

  Molecular Pharmacology November 2015, 88 (5) 881-893; DOI: https://doi.org/10.1124/mol.115.100982
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  Selectivity in the Use of G_i/o Proteins Is Determined by the DRF Motif in CXCR6 and Is Cell-Type Specific

  Satya P. Singh, John F. Foley, Hongwei H. Zhang, Darrell E. Hurt, Jennifer L. Richards, Craig S. Smith, Fang Liao and Joshua M. Farber

  Molecular Pharmacology November 2015, 88 (5) 894-910; DOI: https://doi.org/10.1124/mol.115.099960
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  GPR139, an Orphan Receptor Highly Enriched in the Habenula and Septum, Is Activated by the Essential Amino Acids l-Tryptophan and l-Phenylalanine

  Changlu Liu, Pascal Bonaventure, Grace Lee, Diane Nepomuceno, Chester Kuei, Jiejun Wu, Qingqin Li, Victory Joseph, Steven W. Sutton, William Eckert, Xiang Yao, Lynn Yieh, Curt Dvorak, Nicholas Carruthers, Heather Coate, Sujin Yun, Christine Dugovic, Anthony Harrington and Timothy W. Lovenberg

  Molecular Pharmacology November 2015, 88 (5) 911-925; DOI: https://doi.org/10.1124/mol.115.100412
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  Breathing Stimulant Compounds Inhibit TASK-3 Potassium Channel Function Likely by Binding at a Common Site in the Channel Pore

  Rikki H. Chokshi, Aaron T. Larsen, Brijesh Bhayana and Joseph F. Cotten

  Molecular Pharmacology November 2015, 88 (5) 926-934; DOI: https://doi.org/10.1124/mol.115.100107
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  Identification of a Highly Conserved Allosteric Binding Site on Mnk1 and Mnk2

  Sunita K.C. Basnet, Sarah Diab, Raffaella Schmid, Mingfeng Yu, Yuchao Yang, Todd Alexander Gillam, Theodosia Teo, Peng Li, Tom Peat, Hugo Albrecht and Shudong Wang

  Molecular Pharmacology November 2015, 88 (5) 935-948; DOI: https://doi.org/10.1124/mol.115.100131
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  Gedunin Binds to Myeloid Differentiation Protein 2 and Impairs Lipopolysaccharide-Induced Toll-Like Receptor 4 Signaling in Macrophages

  Perla Villani Borges, Katelim Hottz Moret, Clarissa Menezes Maya-Monteiro, Franklin Souza-Silva, Carlos Roberto Alves, Paulo Ricardo Batista, Ernesto Raúl Caffarena, Patrícia Pacheco, Maria das Graças Henriques and Carmen Penido

  Molecular Pharmacology November 2015, 88 (5) 949-961; DOI: https://doi.org/10.1124/mol.115.098970