About the cover: Image shows expression of fluorescently stained S1PR3-A555 (red) and DAPI for nuclei (blue) on a single cardiac Purkinje fiber rendered and reconstructed using IMARIS software (Bitplance Inc.) from confocal images obtained with laser scanning confocal microscope (Zeiss Inc.) on a 40 micron section from mouse cardiac heart tissue. See the article by Rosen et al. (dx.doi.org/10.1124/mol.115.100222).