Table of Contents

Articles

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  Differential Regulation of Human Ether-à-Go-Go–Related Gene (hERG) Current and Expression by Activation of Protein Kinase C

  Morgan E. Sutherland-Deveen, Tingzhong Wang, Shawn M. Lamothe, Jared N. Tschirhart, Jun Guo, Wentao Li, Tonghua Yang, Yuan Du and Shetuan Zhang

  Molecular Pharmacology July 2019, 96 (1) 1-12; DOI: https://doi.org/10.1124/mol.118.115188
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  Identification of MRP4/ABCC4 as a Target for Reducing the Proliferation of Pancreatic Ductal Adenocarcinoma Cells by Modulating the cAMP Efflux

  Alejandro Carozzo, Agustín Yaneff, Natalia Gómez, Nicolás Di Siervi, Ana Sahores, Federico Diez, Alejandra I. Attorresi, Ángela Rodríguez-González, Federico Monczor, Natalia Fernández, Martín Abba, Carina Shayo and Carlos Davio

  Molecular Pharmacology July 2019, 96 (1) 13-25; DOI: https://doi.org/10.1124/mol.118.115444
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  A Small-Molecule Compound Selectively Activates K2P Channel TASK-3 by Acting at Two Distant Clusters of Residues

  Fuyun Tian, Yunguang Qiu, Xi Lan, Min Li, Huaiyu Yang and Zhaobing Gao

  Molecular Pharmacology July 2019, 96 (1) 26-35; DOI: https://doi.org/10.1124/mol.118.115303
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  Identifying the ErbB/MAPK Signaling Cascade as a Therapeutic Target in Canine Bladder Cancer

  Kathryn E. Cronise, Belen G. Hernandez, Daniel L. Gustafson and Dawn L. Duval

  Molecular Pharmacology July 2019, 96 (1) 36-46; DOI: https://doi.org/10.1124/mol.119.115808
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  Hepatic Expression of Niemann-Pick C1-Like 1, a Cholesterol Reabsorber from Bile, Exacerbates Western Diet–Induced Atherosclerosis in LDL Receptor Mutant Mice

  Hideaki Yamamoto, Yoshihide Yamanashi, Tappei Takada, Shuang Mu, Yusuke Tanaka, Toko Komine and Hiroshi Suzuki

  Molecular Pharmacology July 2019, 96 (1) 47-55; DOI: https://doi.org/10.1124/mol.119.115840
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  Impact of Phosphodiesterase 4 Inhibition on the Operational Efficacy, Response Maxima, and Kinetics of Indacaterol-Induced Gene Expression Changes in BEAS-2B Airway Epithelial Cells: A Global Transcriptomic Analysis

  Radhika Joshi, Dong Yan, Omar Hamed, Mahmoud M. Mostafa, Taruna Joshi, Robert Newton and Mark A. Giembycz

  Molecular Pharmacology July 2019, 96 (1) 56-72; DOI: https://doi.org/10.1124/mol.118.115311
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  Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy

  Kinsie E. Arnst, Yuxi Wang, Zi-Ning Lei, Dong-Jin Hwang, Gyanendra Kumar, Dejian Ma, Deanna N. Parke, Qiang Chen, Jinliang Yang, Stephen W. White, Tiffany N. Seagroves, Zhe-Sheng Chen, Duane D. Miller and Wei Li

  Molecular Pharmacology July 2019, 96 (1) 73-89; DOI: https://doi.org/10.1124/mol.118.114801
• Open Access

  Small Fluorescein Arsenical Hairpin–Based Förster Resonance Energy Transfer Analysis Reveals Changes in Amino- to Carboxyl-Terminal Interactions upon OAG Activation of Classical Transient Receptor Potential 6

  Susanne Fiedler, Ursula Storch, Serap Erdogmus, Thomas Gudermann, Michael Mederos y Schnitzler and Alexander Dietrich

  Molecular Pharmacology July 2019, 96 (1) 90-98; DOI: https://doi.org/10.1124/mol.119.115949
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  Active-Site Tryptophan, the Target of Antineoplastic C-Terminal Binding Protein Inhibitors, Mediates Inhibitor Disruption of CtBP Oligomerization and Transcription Coregulatory Activities

  M. Michael Dcona, Priyadarshan K. Damle, Francisco Zarate-Perez, Benjamin L. Morris, Zaid Nawaz, Michael J. Dennis, Xiaoyan Deng, Sudha Korwar, Sahib J. Singh, Keith C. Ellis, William E. Royer, Dipankar Bandyopadhyay, Carlos Escalante and Steven R. Grossman

  Molecular Pharmacology July 2019, 96 (1) 99-108; DOI: https://doi.org/10.1124/mol.118.114363
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  Preferred Formation of Heteromeric Channels between Coexpressed SK1 and IKCa Channel Subunits Provides a Unique Pharmacological Profile of Ca²⁺-Activated Potassium Channels

  James Higham, Giriraj Sahu, Rima-Marie Wazen, Pina Colarusso, Alice Gregorie, Bartholomew S. J. Harvey, Lucy Goudswaard, Gemma Varley, David N. Sheppard, Ray W. Turner and Neil V. Marrion

  Molecular Pharmacology July 2019, 96 (1) 115-126; DOI: https://doi.org/10.1124/mol.118.115634