Article Information
PubMed
Print ISSN
Online ISSN
History
- Received November 16, 2021
- Accepted February 22, 2022
- Published online April 7, 2022.
Article Versions
- Earlier version (March 3, 2022 - 23:20).
- You are viewing the most recent version of this article.
Copyright & Usage
Copyright © 2022 by The American Society for Pharmacology and Experimental Therapeutics
Author Information
- Shalini Dogra and
- P. Jeffrey Conn
- Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee
- Address Correspondence to:
Dr. P. Jeffrey Conn, Professor of Pharmacology, Founding Director and Director Emeritus, Warren Center for Neuroscience Drug Discovery, Vanderbilt University, 1205 Light Hall, Nashville, TN 37232-0697. E-mail: jeff.conn{at}vanderbilt.edu
Statistics from Altmetric.com
Article usage
In this issue
Jump to section
- Article
- Abstract
- Introduction
- Genomic Variants in GRM5 and mGlu5 Receptor Hypofunction Are Associated with Schizophrenia
- mGlu5 Potentiators Reduce Behavioral Disruptions That Are Relevant for Schizophrenia in Rodent Models
- Biased mGlu5 Receptor PAMs That Do Not Potentiate Coupling of mGlu5 Receptors to NMDA Receptors or Exert Allosteric Agonist Activity Do Not Induce Observable Adverse Effects
- mGlu1 Receptor PAMs May Have Potential Antipsychotic Effects
- The mGlu1 Receptor Ligands Display Antipsychotic-Like Effects in Rodents
- Group II (mGlu2/3) Receptor Agonists Show Efficacy for Treating Behavioral Correlates of Schizophrenia
- Clinical Trials Using mGlu2/3 Receptor Agonists Yielded Inconclusive Results
- mGlu2 Receptor PAMs May Have Potential Antipsychotic Activity
- Genetic Variants in GRM3 Are Associated with Schizophrenia
- mGlu3 Receptor Is a Promising Target for Enhancing Cognition in Schizophrenia
- mGlu4 Receptor Ligands Have the Potential To Treat Positive Symptoms of Schizophrenia
- Potential Utility of mGlu2-mGlu4 Receptor Heterodimers As Novel Antipsychotics
- Deletion or Blockade of mGlu7 Receptor Impairs Cognition
- mGlu7 Receptor NAMs Can Rescue Schizophrenia-Like Symptoms in Rodents
- Deletion of GRM8 Does Not Induce Consistent Endophenotypes of Schizophrenia
- Concluding Remarks
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Info & Metrics
- eLetters
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement