Abstract
Dopamine β-hydroxylase activity in the adrenal medulla is decreased 1 week after hypophysectomy. This activity can be restored by treatment with either adrenocorticotropin or dexamethasone. Adrenal denervation also decreases adrenal dopamine β-hydroxylase activity and prevents elevation of this enzyme in response to immobilization. Intact pituitary-adrenal and neuronal systems are required to maintain normal adrenal dopamine β-hydroxylase levels nonimmobilized rats and to raise the levels in immobilized rats.
ACKNOWLEDGMENT We are grateful to Mrs. Darina Kvetňanská for her excellent technical assistance.
- Copyright ©, 1971, by Academic Press, Inc.
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