Data Supplement

Files in this Data Supplement:

• Figure S1 - Intravenously injected 8D3 MAbs specifically labeled brain microvessels after intravenous injection.
• Figure S2 - Confirmation of the presence of TfR on both microvessels and neurons as measured with Ri7 immunohistofluorescence.
• Figure S3 - Line profile plot of the distribution of the anti-TfR MAb Ri7 suggests a luminal, endothelial, and abluminal distribution in brain microvessels.
• Movie S1 Legend - Evidence of internalization within brain microvessels of fluorolabeled MAbs targeting the TfR.
• Movie S1